Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STYX
  • Mouse genes Styx
  • Rat genes Styx
  • Zfish genes styx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Styx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990444	F-box domain binding	STYX	IMP	UniProtKB:Q969H0-1	Human	PMID:28007894
Molecular Function	GO:0005515	protein binding	STYX	IPI	UniProtKB:P28482	Human	PMID:23847209
Molecular Function	GO:0005515	protein binding	STYX	IPI	UniProtKB:Q969H0	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	STYX	IPI	UniProtKB:Q969H0	Human	PMID:28007894
Molecular Function	GO:0005515	protein binding	STYX	IPI	UniProtKB:Q969H0-1	Human	PMID:28007894
Molecular Function	GO:0005515	protein binding	STYX	IPI	UniProtKB:Q969H0-1|UniProtKB:Q969H0-4	Human	PMID:28007894
Molecular Function	GO:0005515	protein binding	Styx	IPI	PR:Q9CR86	Mouse	PMID:11842224
Molecular Function	GO:0001691	pseudophosphatase activity	STYX	IMP		Human	PMID:28007894
Cellular Component	GO:0005737	cytoplasm	STYX	IDA		Human	PMID:23847209
Cellular Component	GO:0005737	cytoplasm	Styx	IDA		Mouse	PMID:11842224
Cellular Component	GO:0005654	nucleoplasm	STYX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	STYX	IDA		Human	PMID:23847209
Cellular Component	GO:0005634	nucleus	STYX	IDA		Human	PMID:28007894
Biological Process	GO:0045204	MAPK export from nucleus	STYX	IMP		Human	PMID:23847209
Biological Process	GO:0032091	negative regulation of protein binding	STYX	IDA		Human	PMID:28007894
Biological Process	GO:0062026	negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process	STYX	IMP		Human	PMID:28007894
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	STYX	IMP		Human	PMID:23847209
Biological Process	GO:0007283	spermatogenesis	Styx	IMP	MGI:MGI:2179177	Mouse	PMID:11842224

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern