Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ST18
  • Mouse genes St18
  • Rat genes St18
  • Zfish genes st18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set St18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	St18	IDA		Rat	PMID:9478997|RGD:1299533
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ST18	IDA		Human	PMID:18676404
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	St18	IDA		Rat	PMID:9478997|RGD:1299533
Cellular Component	GO:0005634	nucleus	ST18	IDA		Human	PMID:15489893
Cellular Component	GO:0005634	nucleus	St18	IDA		Rat	PMID:9478997|RGD:1299533
Cellular Component	GO:0032993	protein-DNA complex	ST18	IDA		Human	PMID:18676404
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	ST18	IMP		Human	PMID:18676404
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	ST18	IMP		Human	PMID:18676404
Biological Process	GO:0008285	negative regulation of cell population proliferation	ST18	IDA		Human	PMID:15489893
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	St18	IMP		Rat	PMID:9478997|RGD:1299533
Biological Process	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	ST18	IMP		Human	PMID:18676404
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ST18	IMP		Human	PMID:18676404
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	ST18	IMP		Human	PMID:18676404

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern