Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRSF6
  • Mouse genes Srsf6
  • Rat genes Srsf6
  • Zfish genes srsf6a,srsf6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srsf6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036002	pre-mRNA binding	SRSF6	IDA		Human	PMID:12549914
Molecular Function	GO:0005515	protein binding	SRSF6	IPI	UniProtKB:Q9Y383	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRSF6	IPI	UniProtKB:Q9Y383	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SRSF6	IPI	UniProtKB:Q9NQ29-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRSF6	IPI	UniProtKB:Q9Y383	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Srsf6	IPI	UniProtKB:O41974	Mouse	MGI:MGI:5787727|PMID:26581985
Molecular Function	GO:0003723	RNA binding	SRSF6	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SRSF6	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	SRSF6	IDA		Human	PMID:24440982
Cellular Component	GO:0016607	nuclear speck	SRSF6	IDA		Human	PMID:22767602
Cellular Component	GO:0005634	nucleus	Srsf6	IDA		Rat	PMID:23233666|RGD:10059618
Biological Process	GO:0000380	alternative mRNA splicing, via spliceosome	SRSF6	IDA		Human	PMID:22767602
Biological Process	GO:0006376	mRNA splice site selection	SRSF6	IMP		Human	PMID:12549914
Biological Process	GO:0060548	negative regulation of cell death	SRSF6	IDA		Human	PMID:23132731
Biological Process	GO:0010629	negative regulation of gene expression	Srsf6	IMP		Rat	PMID:23737756|RGD:11039479
Biological Process	GO:0045617	negative regulation of keratinocyte differentiation	SRSF6	IMP		Human	PMID:24440982
Biological Process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	SRSF6	IDA		Human	PMID:15009664
Biological Process	GO:2000675	negative regulation of type B pancreatic cell apoptotic process	Srsf6	IMP		Rat	PMID:23737756|RGD:11039479
Biological Process	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	SRSF6	IDA		Human	PMID:23132731
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	SRSF6	IDA		Human	PMID:23132731
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	SRSF6	IMP		Human	PMID:24440982
Biological Process	GO:0010837	regulation of keratinocyte proliferation	SRSF6	IMP		Human	PMID:24440982
Biological Process	GO:0061041	regulation of wound healing	SRSF6	IMP		Human	PMID:24440982
Biological Process	GO:0032868	response to insulin	Srsf6	IEP		Rat	PMID:11283022|RGD:11039459

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern