About   Help   FAQ
Srsf6 Gene Detail
Summary
  • Symbol
    Srsf6
  • Name
    serine/arginine-rich splicing factor 6
  • Synonyms
    1210001E11Rik, Sfrs6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915246
    NCBI Gene: 67996
  • Gene Overview
    MyGene.info: SRSF6
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:162931528-162937121 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 83.87 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915246
protein coding gene Chr2:162931508-162937121 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026813
protein coding gene Chr2:168209371-168214963 (+)
A/J MGP_AJ_G0026779
protein coding gene Chr2:161465419-161471012 (+)
AKR/J MGP_AKRJ_G0026750
protein coding gene Chr2:166221985-166230541 (+)
BALB/cJ MGP_BALBcJ_G0026788
protein coding gene Chr2:161784663-161790256 (+)
C3H/HeJ MGP_C3HHeJ_G0026530
protein coding gene Chr2:166571570-166578477 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027236
protein coding gene Chr2:173159180-173164774 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024606
protein coding gene Chr2:154759664-154765028 (+)
CAST/EiJ MGP_CASTEiJ_G0025991
protein coding gene Chr2:166931298-166936893 (+)
CBA/J MGP_CBAJ_G0026507
protein coding gene Chr2:179408259-179418641 (+)
DBA/2J MGP_DBA2J_G0026645
protein coding gene Chr2:160634991-160641200 (+)
FVB/NJ MGP_FVBNJ_G0026611
protein coding gene Chr2:159004375-159009882 (+)
LP/J MGP_LPJ_G0026748
protein coding gene Chr2:168358719-168364311 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026633
protein coding gene Chr2:183103777-183109371 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027292
protein coding gene Chr2:166104694-166110288 (+)
PWK/PhJ MGP_PWKPhJ_G0025725
protein coding gene Chr2:160177206-160183018 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025528
protein coding gene Chr2:164976791-164984160 (+)
WSB/EiJ MGP_WSBEiJ_G0026061
protein coding gene Chr2:166975376-166980968 (+)



Homology
more
  • Human Ortholog
    SRSF6, serine and arginine rich splicing factor 6
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SRSF6, serine and arginine rich splicing factor 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    B52, HEL-S-91, SFRS6, SRP55
  • Links
    NCBI Gene ID: 6431
    neXtProt AC: NX_Q13247
    UniProt: Q13247

  • Chr Location
    20q13.11; chr20:43457864-43463605 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016921 Ensembl Gene Model | MGI Sequence Detail 5594 C57BL/6J ±  kb
transcript ENSMUST00000130411 Ensembl | MGI Sequence Detail 3527 Not Applicable  
polypeptide ENSMUSP00000119065 Ensembl | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 2
    cDNA 17
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:2138887, MGI:2147715, MGI:2152843
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:66467 Pazzaglia S, et al., Somatic cell hybrids for high-density mapping of chromosome 2 breakpoints in radiation-induced myeloid leukemia cell lines from inbred mice. Mol Carcinog. 2000 Mar;27(3):219-28
  • Latest
    J:256883 Zhou J, et al., Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/13/2018
MGI 6.13
The Jackson Laboratory