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Srsf6 Gene Detail
Summary
  • Symbol
    Srsf6
  • Name
    serine/arginine-rich splicing factor 6
  • Synonyms
    1210001E11Rik, Sfrs6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915246
    NCBI Gene: 67996
  • Gene Overview
    MyGene.info: SRSF6
Location & Maps
more
  • Sequence Map
    Chr2:162931528-162937121 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5594 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 83.87 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SRSF6, serine and arginine rich splicing factor 6
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SRSF6, serine and arginine rich splicing factor 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    B52, HEL-S-91, SFRS6, SRP55
  • Links
    NCBI Gene ID: 6431
    neXtProt AC: NX_Q13247

  • Chr Location
    20q12-q13.1; chr20:43457864-43463605 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    8
  • Gene trapped
    7
  • Targeted
    1
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001060 VEGA Gene Model | MGI Sequence Detail 5594 C57BL/6J ±  kb
transcript OTTMUST00000002102 VEGA | MGI Sequence Detail 3527 Not Applicable  
polypeptide OTTMUSP00000001014 VEGA | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    26 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000014763 serine/arginine-rich splicing factor 6
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
Molecular
Reagents
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  • All nucleic 19
    Genomic 2
    cDNA 16
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
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MGI:2138887, MGI:2147715, MGI:2152843
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:66467 Pazzaglia S, et al., Somatic cell hybrids for high-density mapping of chromosome 2 breakpoints in radiation-induced myeloid leukemia cell lines from inbred mice. Mol Carcinog. 2000 Mar;27(3):219-28
  • Latest
    J:233627 Salinas E, et al., Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. J Virol. 2016 Feb;90(3):1397-413

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory