Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRPX
  • Mouse genes Srpx
  • Rat genes Srpx
  • Zfish genes srpx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srpx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SRPX	IPI	UniProtKB:Q9BRX2	Human	PMID:20406461
Molecular Function	GO:0005515	protein binding	Srpx	IPI	PR:P51150	Mouse	PMID:19368996
Molecular Function	GO:0005515	protein binding	Srpx	IPI	PR:P35290	Mouse	PMID:19368996
Molecular Function	GO:0005515	protein binding	Srpx	IPI	PR:P35292	Mouse	PMID:19368996
Molecular Function	GO:0005515	protein binding	Srpx	IPI	PR:P35282	Mouse	PMID:19368996
Cellular Component	GO:0005776	autophagosome	Srpx	IDA		Mouse	PMID:19368996
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SRPX	HDA		Human	PMID:25037231
Cellular Component	GO:0005783	endoplasmic reticulum	Srpx	IDA		Mouse	PMID:19368996
Biological Process	GO:0006914	autophagy	Srpx	IMP	MGI:MGI:3706175	Mouse	PMID:19368996
Biological Process	GO:0060244	negative regulation of cell proliferation involved in contact inhibition	Srpx	IDA		Mouse	PMID:12049817
Biological Process	GO:0001845	phagolysosome assembly	Srpx	IMP	MGI:MGI:3706175	Mouse	PMID:19368996
Biological Process	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Srpx	IMP	MGI:MGI:3706175	Mouse	PMID:17088259
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Srpx	IMP	MGI:MGI:3706175	Mouse	PMID:17088259

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern