Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPRTN
  • Mouse genes Sprtn
  • Rat genes Sprtn
  • Zfish genes sprtn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sprtn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003690	double-stranded DNA binding	SPRTN	IDA		Human	PMID:27852435
Molecular Function	GO:0003690	double-stranded DNA binding	SPRTN	IDA		Human	PMID:27871365
Molecular Function	GO:0003690	double-stranded DNA binding	SPRTN	IDA		Human	PMID:27871366
Molecular Function	GO:0003690	double-stranded DNA binding	SPRTN	IDA		Human	PMID:32649882
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	SPRTN	IDA		Human	PMID:22681887
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	SPRTN	IDA		Human	PMID:23042605
Molecular Function	GO:0004222	metalloendopeptidase activity	SPRTN	IDA		Human	PMID:27852435
Molecular Function	GO:0004222	metalloendopeptidase activity	SPRTN	IDA		Human	PMID:27871365
Molecular Function	GO:0004222	metalloendopeptidase activity	SPRTN	IDA		Human	PMID:27871366
Molecular Function	GO:0004222	metalloendopeptidase activity	SPRTN	IDA		Human	PMID:32649882
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:P12004	Human	PMID:22681887
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:Q9NS91	Human	PMID:22681887
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:P12004	Human	PMID:22894931
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:P12004	Human	PMID:22902628
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:P55072	Human	PMID:22902628
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:P12004	Human	PMID:23042605
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:P55072	Human	PMID:23042605
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:P12004	Human	PMID:23042607
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:P55072	Human	PMID:23042607
Molecular Function	GO:0005515	protein binding	SPRTN	IPI	UniProtKB:O00629	Human	PMID:35044719
Molecular Function	GO:0003697	single-stranded DNA binding	SPRTN	IDA		Human	PMID:27871365
Molecular Function	GO:0003697	single-stranded DNA binding	SPRTN	IDA		Human	PMID:32649882
Molecular Function	GO:0043130	ubiquitin binding	SPRTN	IDA		Human	PMID:22681887
Molecular Function	GO:0043130	ubiquitin binding	SPRTN	IDA		Human	PMID:22894931
Molecular Function	GO:0043130	ubiquitin binding	SPRTN	IDA		Human	PMID:22902628
Molecular Function	GO:0043130	ubiquitin binding	SPRTN	IDA		Human	PMID:23042605
Molecular Function	GO:0043130	ubiquitin binding	SPRTN	IDA		Human	PMID:23042607
Cellular Component	GO:0000785	chromatin	SPRTN	IDA		Human	PMID:27852435
Cellular Component	GO:0000785	chromatin	SPRTN	IDA		Human	PMID:27871365
Cellular Component	GO:0000785	chromatin	SPRTN	IDA		Human	PMID:27871366
Cellular Component	GO:0000785	chromatin	SPRTN	IDA		Human	PMID:32649882
Cellular Component	GO:0016607	nuclear speck	SPRTN	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005654	nucleoplasm	SPRTN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SPRTN	IDA		Human	PMID:22681887
Cellular Component	GO:0005634	nucleus	SPRTN	IDA		Human	PMID:22894931
Cellular Component	GO:0005634	nucleus	SPRTN	IDA		Human	PMID:23042605
Cellular Component	GO:0005634	nucleus	SPRTN	IDA		Human	PMID:23042607
Cellular Component	GO:0005634	nucleus	SPRTN	IDA		Human	PMID:27852435
Biological Process	GO:0006974	DNA damage response	SPRTN	IDA		Human	PMID:22681887
Biological Process	GO:0006974	DNA damage response	SPRTN	IDA		Human	PMID:22894931
Biological Process	GO:0006974	DNA damage response	SPRTN	IDA		Human	PMID:22902628
Biological Process	GO:0006974	DNA damage response	SPRTN	IDA		Human	PMID:23042605
Biological Process	GO:0006974	DNA damage response	SPRTN	IDA		Human	PMID:23042607
Biological Process	GO:0006974	DNA damage response	SPRTN	IDA		Human	PMID:27852435
Biological Process	GO:0006974	DNA damage response	SPRTN	IDA		Human	PMID:27871365
Biological Process	GO:0006974	DNA damage response	SPRTN	IDA		Human	PMID:27871366
Biological Process	GO:0006974	DNA damage response	SPRTN	IDA		Human	PMID:32649882
Biological Process	GO:0006974	DNA damage response	sprtn	IMP	ZFIN:ZDB-MRPHLNO-170410-3	Zfish	PMID:25261934
Biological Process	GO:0031398	positive regulation of protein ubiquitination	SPRTN	IDA		Human	PMID:22681887
Biological Process	GO:0016540	protein autoprocessing	SPRTN	IDA		Human	PMID:27852435
Biological Process	GO:0016540	protein autoprocessing	SPRTN	IDA		Human	PMID:27871365
Biological Process	GO:0016540	protein autoprocessing	SPRTN	IDA		Human	PMID:27871366
Biological Process	GO:0016540	protein autoprocessing	SPRTN	IDA		Human	PMID:32649882
Biological Process	GO:0106300	protein-DNA covalent cross-linking repair	SPRTN	IDA		Human	PMID:27852435
Biological Process	GO:0106300	protein-DNA covalent cross-linking repair	SPRTN	IDA		Human	PMID:27871365
Biological Process	GO:0106300	protein-DNA covalent cross-linking repair	SPRTN	IDA		Human	PMID:27871366
Biological Process	GO:0106300	protein-DNA covalent cross-linking repair	SPRTN	IDA		Human	PMID:32152270
Biological Process	GO:0106300	protein-DNA covalent cross-linking repair	SPRTN	IDA		Human	PMID:32649882
Biological Process	GO:0106300	protein-DNA covalent cross-linking repair	Sprtn	IMP		Mouse	MGI:MGI:5922101|PMID:28199696
Biological Process	GO:0006508	proteolysis	SPRTN	IDA		Human	PMID:27852435
Biological Process	GO:0006508	proteolysis	SPRTN	IDA		Human	PMID:27871365
Biological Process	GO:0006508	proteolysis	SPRTN	IDA		Human	PMID:27871366
Biological Process	GO:0006508	proteolysis	SPRTN	IDA		Human	PMID:32649882
Biological Process	GO:0009411	response to UV	SPRTN	IDA		Human	PMID:22681887
Biological Process	GO:0009411	response to UV	SPRTN	IDA		Human	PMID:22894931
Biological Process	GO:0009411	response to UV	SPRTN	IDA		Human	PMID:22902628
Biological Process	GO:0019985	translesion synthesis	SPRTN	IDA		Human	PMID:22681887
Biological Process	GO:0019985	translesion synthesis	SPRTN	IDA		Human	PMID:22902628
Biological Process	GO:0019985	translesion synthesis	SPRTN	IMP		Human	PMID:23042605
Biological Process	GO:0019985	translesion synthesis	SPRTN	IMP		Human	PMID:23042607

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern