Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPON1
  • Mouse genes Spon1
  • Rat genes Spon1
  • Zfish genes spon1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spon1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050693	LBD domain binding	Spon1	IPI	PR:Q924X6	Mouse	PMID:16227578
Molecular Function	GO:0005515	protein binding	SPON1	IPI	UniProtKB:P05067-4	Human	PMID:14983046
Molecular Function	GO:0005515	protein binding	SPON1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPON1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPON1	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Spon1	IPI	PR:P12023	Mouse	PMID:16227578
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SPON1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Spon1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0005615	extracellular space	SPON1	HDA		Human	PMID:20551380
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	Spon1	IDA		Mouse	PMID:16227578
Biological Process	GO:1902993	positive regulation of amyloid precursor protein catabolic process	Spon1	IDA		Mouse	PMID:16227578
Biological Process	GO:0032092	positive regulation of protein binding	Spon1	IDA		Mouse	PMID:16227578
Biological Process	GO:0010954	positive regulation of protein processing	Spon1	IDA		Mouse	PMID:16227578
Biological Process	GO:0016485	protein processing	Spon1	IDA		Mouse	PMID:16227578

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern