Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPDYA
  • Mouse genes Spdya
  • Rat genes Spdya
  • Zfish genes spdya
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spdya

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPDYA	IPI	UniProtKB:P29972	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPDYA	IPI	UniProtKB:P46527	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPDYA	IPI	UniProtKB:Q00535	Human	PMID:32296183
Molecular Function	GO:0030295	protein kinase activator activity	SPDYA	IDA		Human	PMID:28666995
Molecular Function	GO:0030295	protein kinase activator activity	Spdya	IDA		Mouse	PMID:28031483
Molecular Function	GO:0019901	protein kinase binding	SPDYA	IPI	UniProtKB:P24941	Human	PMID:11980914
Molecular Function	GO:0019901	protein kinase binding	SPDYA	IPI	UniProtKB:P24941	Human	PMID:12839962
Molecular Function	GO:0019901	protein kinase binding	SPDYA	IPI	UniProtKB:P24941	Human	PMID:28666995
Molecular Function	GO:0019901	protein kinase binding	Spdya	IPI	UniProtKB:P24033|UniProtKB:P24941|UniProtKB:P35567	Mouse	MGI:MGI:3617485|PMID:15611625
Molecular Function	GO:0019901	protein kinase binding	Spdya	IPI	PR:P97377	Mouse	PMID:28031483
Cellular Component	GO:0000781	chromosome, telomeric region	Spdya	IDA		Mouse	PMID:28031483
Cellular Component	GO:0000781	chromosome, telomeric region	Spdya	IDA		Mouse	PMID:30718482
Cellular Component	GO:0005635	nuclear envelope	Spdya	IDA		Mouse	PMID:28031483
Cellular Component	GO:0005654	nucleoplasm	SPDYA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SPDYA	IDA		Human	PMID:11980914
Cellular Component	GO:0005634	nucleus	Spdya	IDA		Mouse	MGI:MGI:5437430|PMID:20339383
Cellular Component	GO:0001741	XY body	Spdya	IDA		Mouse	PMID:28031483
Biological Process	GO:0006974	DNA damage response	SPDYA	IDA		Human	PMID:12839962
Biological Process	GO:0070200	establishment of protein localization to telomere	Spdya	IMP	MGI:MGI:5888863	Mouse	PMID:28031483
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	SPDYA	IDA		Human	PMID:11980914
Biological Process	GO:0007140	male meiotic nuclear division	Spdya	IEP		Mouse	MGI:MGI:5437430|PMID:20339383
Biological Process	GO:0070197	meiotic attachment of telomere to nuclear envelope	Spdya	IDA		Mouse	PMID:28031483
Biological Process	GO:0070197	meiotic attachment of telomere to nuclear envelope	Spdya	IMP	MGI:MGI:5888863	Mouse	PMID:28031483
Biological Process	GO:0048477	oogenesis	Spdya	IMP	MGI:MGI:5888863	Mouse	PMID:28031483
Biological Process	GO:0008284	positive regulation of cell population proliferation	SPDYA	IDA		Human	PMID:11980914
Biological Process	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	Spdya	IDA		Mouse	MGI:MGI:3617485|PMID:15611625
Biological Process	GO:0045860	positive regulation of protein kinase activity	SPDYA	IDA		Human	PMID:28666995
Biological Process	GO:0045860	positive regulation of protein kinase activity	Spdya	IDA		Mouse	PMID:28031483
Biological Process	GO:0007283	spermatogenesis	Spdya	IMP	MGI:MGI:5888863	Mouse	PMID:28031483
Biological Process	GO:0016233	telomere capping	Spdya	IMP	MGI:MGI:5888863	Mouse	PMID:28031483

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern