Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPAG9
  • Mouse genes Spag9
  • Rat genes Spag9
  • Zfish genes spag9a,spag9b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spag9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Spag9	IPI	PR:Q58A65	Mouse	PMID:15767678
Molecular Function	GO:0008432	JUN kinase binding	Spag9	IDA		Mouse	PMID:15767678
Molecular Function	GO:0019894	kinesin binding	Spag9	IDA		Mouse	PMID:15767678
Molecular Function	GO:0005078	MAP-kinase scaffold activity	Spag9	IDA		Mouse	PMID:15767678
Molecular Function	GO:0005515	protein binding	SPAG9	IPI	UniProtKB:P62330	Human	PMID:19644450
Molecular Function	GO:0005515	protein binding	SPAG9	IPI	UniProtKB:P84077	Human	PMID:19644450
Molecular Function	GO:0005515	protein binding	SPAG9	IPI	UniProtKB:P62331	Human	PMID:22522702
Molecular Function	GO:0005515	protein binding	SPAG9	IPI	UniProtKB:Q96A65	Human	PMID:25244576
Molecular Function	GO:0005515	protein binding	SPAG9	IPI	UniProtKB:P61006	Human	PMID:29125462
Molecular Function	GO:0005515	protein binding	SPAG9	IPI	UniProtKB:P61006	Human	PMID:32017888
Molecular Function	GO:0005515	protein binding	Spag9	IPI	UniProtKB:P62331	Mouse	MGI:MGI:4457975|PMID:20493856
Molecular Function	GO:0005515	protein binding	Spag9	IPI	UniProtKB:Q5S007	Mouse	MGI:MGI:5487757|PMID:20173330
Molecular Function	GO:0005515	protein binding	Spag9	IPI	PR:O35099	Mouse	PMID:15767678
Molecular Function	GO:0005515	protein binding	Spag9	IPI	UniProtKB:P61244	Mouse	PMID:12391307
Molecular Function	GO:0005515	protein binding	Spag9	IPI	UniProtKB:P01106	Mouse	PMID:12391307
Cellular Component	GO:0034451	centriolar satellite	SPAG9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	Spag9	IDA		Mouse	PMID:15767678
Cellular Component	GO:0005829	cytosol	SPAG9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	SPAG9	HDA		Human	PMID:19056867
Cellular Component	GO:0005765	lysosomal membrane	SPAG9	IDA		Human	PMID:29146937
Biological Process	GO:0032418	lysosome localization	SPAG9	IMP		Human	PMID:29146937
Biological Process	GO:1903860	negative regulation of dendrite extension	Spag9	IMP		Rat	PMID:19959466|RGD:30296662
Biological Process	GO:0045665	negative regulation of neuron differentiation	Spag9	IMP		Rat	PMID:19959466|RGD:30296662
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Spag9	IMP		Rat	PMID:19959466|RGD:30296662
Biological Process	GO:0030335	positive regulation of cell migration	SPAG9	IMP		Human	PMID:18826971
Biological Process	GO:0043410	positive regulation of MAPK cascade	Spag9	IGI	MGI:MGI:1926387	Mouse	PMID:20004020
Biological Process	GO:0043410	positive regulation of MAPK cascade	Spag9	IGI	MGI:MGI:1346868	Mouse	PMID:15767678
Biological Process	GO:0043410	positive regulation of MAPK cascade	Spag9	IGI	MGI:MGI:1346870	Mouse	PMID:15767678
Biological Process	GO:0043410	positive regulation of MAPK cascade	Spag9	IGI	MGI:MGI:88355	Mouse	PMID:20004020
Biological Process	GO:0043410	positive regulation of MAPK cascade	Spag9	IGI	MGI:MGI:109327	Mouse	PMID:20004020
Biological Process	GO:0043410	positive regulation of MAPK cascade	Spag9	IDA		Mouse	PMID:15767678
Biological Process	GO:0045666	positive regulation of neuron differentiation	Spag9	IMP		Mouse	PMID:19244314
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	SPAG9	IDA		Human	PMID:19056739
Biological Process	GO:0051146	striated muscle cell differentiation	Spag9	IGI	MGI:MGI:1926387	Mouse	PMID:20160094
Biological Process	GO:0051146	striated muscle cell differentiation	Spag9	IGI	MGI:MGI:1346865	Mouse	PMID:20160094
Biological Process	GO:0051146	striated muscle cell differentiation	Spag9	IGI	MGI:MGI:109327	Mouse	PMID:20160094
Biological Process	GO:0051146	striated muscle cell differentiation	Spag9	IGI	MGI:MGI:88355	Mouse	PMID:20160094

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern