Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOAT2
  • Mouse genes Soat2
  • Rat genes Soat2
  • Zfish genes soat2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Soat2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015485	cholesterol binding	SOAT2	IDA		Human	PMID:16647063
Molecular Function	GO:0034736	cholesterol O-acyltransferase activity	SOAT2	IDA		Human	PMID:16647063
Molecular Function	GO:0034736	cholesterol O-acyltransferase activity	soat2	IDA		Zfish	PMID:27936201
Molecular Function	GO:0000062	fatty-acyl-CoA binding	SOAT2	IDA		Human	PMID:16647063
Molecular Function	GO:0005515	protein binding	SOAT2	IPI	UniProtKB:P55061	Human	PMID:32296183
Molecular Function	GO:0004772	sterol O-acyltransferase activity	SOAT2	IDA		Human	PMID:11294643
Molecular Function	GO:0004772	sterol O-acyltransferase activity	Soat2	IDA		Mouse	PMID:9756919
Molecular Function	GO:0004772	sterol O-acyltransferase activity	Soat2	IDA		Rat	PMID:12217884|RGD:625687
Cellular Component	GO:0005903	brush border	SOAT2	IDA		Human	PMID:14615411
Cellular Component	GO:0005783	endoplasmic reticulum	SOAT2	IDA		Human	PMID:15451793
Cellular Component	GO:0005783	endoplasmic reticulum	Soat2	IDA		Rat	PMID:12217884|RGD:625687
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SOAT2	IDA		Human	PMID:12808042
Cellular Component	GO:0016020	membrane	Soat2	IDA		Mouse	PMID:12077311
Cellular Component	GO:0016020	membrane	Soat2	IDA		Mouse	PMID:9756919
Biological Process	GO:0033344	cholesterol efflux	SOAT2	IMP		Human	PMID:15308631
Biological Process	GO:0008203	cholesterol metabolic process	SOAT2	IDA		Human	PMID:11294643
Biological Process	GO:0008203	cholesterol metabolic process	SOAT2	IDA		Human	PMID:16647063
Biological Process	GO:0008203	cholesterol metabolic process	Soat2	IDA		Mouse	PMID:9756919
Biological Process	GO:0008203	cholesterol metabolic process	Soat2	IDA		Rat	PMID:12217884|RGD:625687
Biological Process	GO:0010878	cholesterol storage	Soat2	IGI	MGI:MGI:96789	Mouse	PMID:25450374
Biological Process	GO:0007584	response to nutrient	Soat2	IEP		Rat	PMID:12563020|RGD:1598705
Biological Process	GO:0034379	very-low-density lipoprotein particle assembly	SOAT2	IMP		Human	PMID:15308631

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern