Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOAT1
  • Mouse genes Soat1
  • Rat genes Soat1
  • Zfish genes soat1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Soat1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015485	cholesterol binding	SOAT1	IDA		Human	PMID:16647063
Molecular Function	GO:0015485	cholesterol binding	SOAT1	IDA		Human	PMID:32433613
Molecular Function	GO:0015485	cholesterol binding	SOAT1	IDA		Human	PMID:32433614
Molecular Function	GO:0034736	cholesterol O-acyltransferase activity	SOAT1	IDA		Human	PMID:16647063
Molecular Function	GO:0034736	cholesterol O-acyltransferase activity	SOAT1	IDA		Human	PMID:32433613
Molecular Function	GO:0034736	cholesterol O-acyltransferase activity	SOAT1	IDA		Human	PMID:32433614
Molecular Function	GO:0034736	cholesterol O-acyltransferase activity	SOAT1	IMP		Human	PMID:8407899
Molecular Function	GO:0000062	fatty-acyl-CoA binding	SOAT1	IDA		Human	PMID:16647063
Molecular Function	GO:0005515	protein binding	SOAT1	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	SOAT1	IPI	UniProtKB:Q9Y5Z9	Human	PMID:23169578
Molecular Function	GO:0004772	sterol O-acyltransferase activity	SOAT1	IMP		Human	PMID:8407899
Molecular Function	GO:0004772	sterol O-acyltransferase activity	SOAT1	IMP		Human	PMID:9020103
Molecular Function	GO:0004772	sterol O-acyltransferase activity	SOAT1	IDA		Human	PMID:9756919
Molecular Function	GO:0004772	sterol O-acyltransferase activity	Soat1	IDA		Mouse	PMID:15845870
Molecular Function	GO:0004772	sterol O-acyltransferase activity	Soat1	IDA		Rat	PMID:9555010|RGD:730254
Cellular Component	GO:0005783	endoplasmic reticulum	SOAT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	SOAT1	IDA		Human	PMID:10623671
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SOAT1	IDA		Human	PMID:17412327
Cellular Component	GO:0016020	membrane	SOAT1	IDA		Human	PMID:9756919
Biological Process	GO:0033344	cholesterol efflux	SOAT1	IMP		Human	PMID:15308631
Biological Process	GO:0042632	cholesterol homeostasis	SOAT1	IDA		Human	PMID:32433614
Biological Process	GO:0008203	cholesterol metabolic process	SOAT1	IDA		Human	PMID:9756919
Biological Process	GO:0008203	cholesterol metabolic process	SOAT1	IDA		Human	PMID:16647063
Biological Process	GO:0008203	cholesterol metabolic process	SOAT1	IMP		Human	PMID:8407899
Biological Process	GO:0008203	cholesterol metabolic process	Soat1	IDA		Mouse	PMID:15845870
Biological Process	GO:0010878	cholesterol storage	SOAT1	IMP		Human	PMID:8407899
Biological Process	GO:0010742	macrophage derived foam cell differentiation	SOAT1	IMP		Human	PMID:15353128
Biological Process	GO:0010742	macrophage derived foam cell differentiation	SOAT1	IMP		Human	PMID:8407899
Biological Process	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	SOAT1	IMP		Human	PMID:17412327
Biological Process	GO:0034379	very-low-density lipoprotein particle assembly	SOAT1	IMP		Human	PMID:15308631

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern