Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SNX3
  • Mouse genes Snx3
  • Rat genes Snx3
  • Zfish genes snx3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Snx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	Snx3	IDA		Mouse	MGI:MGI:5607234|PMID:19576982
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	SNX3	IDA		Human	PMID:11433298
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	Snx3	IDA		Mouse	MGI:MGI:5607234|PMID:19576982
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	Snx3	IDA		Mouse	MGI:MGI:5607234|PMID:19576982
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	Snx3	IDA		Mouse	MGI:MGI:5607234|PMID:19576982
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:P46108	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:O75436	Human	PMID:21725319
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:Q96QK1	Human	PMID:21725319
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:Q96QK1	Human	PMID:22719997
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:Q96QK1	Human	PMID:24344282
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:Q9UBQ0	Human	PMID:24344282
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:Q15041	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:Q7Z3U7	Human	PMID:30213940
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:Q96QK1	Human	PMID:30213940
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:Q9Y3R5	Human	PMID:30213940
Molecular Function	GO:0005515	protein binding	SNX3	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Snx3	IPI	PR:Q9JI39	Mouse	PMID:23416069
Molecular Function	GO:0005515	protein binding	Snx3	IPI	PR:Q62351	Mouse	PMID:23416069
Molecular Function	GO:0019903	protein phosphatase binding	SNX3	IPI	UniProtKB:Q92729	Human	PMID:17622474
Molecular Function	GO:1905394	retromer complex binding	SNX3	IDA		Human	PMID:30213940
Cellular Component	GO:0030136	clathrin-coated vesicle	SNX3	IDA		Human	PMID:21725319
Cellular Component	GO:0005737	cytoplasm	SNX3	IDA		Human	PMID:11279102
Cellular Component	GO:0005829	cytosol	SNX3	IDA		Human	PMID:9819414
Cellular Component	GO:0005769	early endosome	SNX3	IDA		Human	PMID:11433298
Cellular Component	GO:0005769	early endosome	SNX3	IDA		Human	PMID:18767904
Cellular Component	GO:0005769	early endosome	SNX3	IDA		Human	PMID:22719997
Cellular Component	GO:0031901	early endosome membrane	SNX3	IDA		Human	PMID:18767904
Cellular Component	GO:0032009	early phagosome	SNX3	IDA		Human	PMID:23237080
Cellular Component	GO:0010008	endosome membrane	SNX3	IDA		Human	PMID:15673616
Cellular Component	GO:0070062	extracellular exosome	SNX3	HDA		Human	PMID:19056867
Biological Process	GO:0030218	erythrocyte differentiation	snx3	IMP	ZFIN:ZDB-MRPHLNO-130524-3	Zfish	PMID:23416069
Biological Process	GO:0030218	erythrocyte differentiation	snx3	IMP	ZFIN:ZDB-MRPHLNO-130524-4	Zfish	PMID:23416069
Biological Process	GO:0006783	heme biosynthetic process	snx3	IMP		Zfish	PMID:23416069|ZFIN:ZDB-PUB-130221-1
Biological Process	GO:0042541	hemoglobin biosynthetic process	Snx3	IMP		Mouse	PMID:23416069
Biological Process	GO:0042541	hemoglobin biosynthetic process	snx3	IMP	ZFIN:ZDB-MRPHLNO-130524-4	Zfish	PMID:23416069
Biological Process	GO:0042541	hemoglobin biosynthetic process	snx3	IMP	ZFIN:ZDB-MRPHLNO-130524-3	Zfish	PMID:23416069
Biological Process	GO:0070676	intralumenal vesicle formation	SNX3	IMP		Human	PMID:18767904
Biological Process	GO:0010324	membrane invagination	SNX3	IDA		Human	PMID:18767904
Biological Process	GO:2000642	negative regulation of early endosome to late endosome transport	SNX3	IDA		Human	PMID:18767904
Biological Process	GO:0050765	negative regulation of phagocytosis	SNX3	IMP		Human	PMID:23237080
Biological Process	GO:0042177	negative regulation of protein catabolic process	SNX3	IDA		Human	PMID:18767904
Biological Process	GO:0051224	negative regulation of protein transport	SNX3	IDA		Human	PMID:18767904
Biological Process	GO:0046597	negative regulation of viral entry into host cell	SNX3	IDA		Human	PMID:18767904
Biological Process	GO:0010976	positive regulation of neuron projection development	Snx3	IMP		Mouse	MGI:MGI:5607234|PMID:19576982
Biological Process	GO:0022615	protein to membrane docking	SNX3	IDA		Human	PMID:24344282
Biological Process	GO:0033157	regulation of intracellular protein transport	Snx3	IMP		Mouse	PMID:23416069
Biological Process	GO:0051246	regulation of protein metabolic process	Snx3	IMP		Mouse	PMID:23416069
Biological Process	GO:0030111	regulation of Wnt signaling pathway	SNX3	IMP		Human	PMID:21725319
Biological Process	GO:0009617	response to bacterium	SNX3	IDA		Human	PMID:20482551
Biological Process	GO:0033572	transferrin transport	Snx3	IMP		Mouse	PMID:23416069

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern