Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMOC2
  • Mouse genes Smoc2
  • Rat genes Smoc2
  • Zfish genes smoc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smoc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Smoc2	IDA		Mouse	MGI:MGI:2670487|PMID:12741954
Molecular Function	GO:0005539	glycosaminoglycan binding	Smoc2	IDA		Mouse	PMID:18757743
Molecular Function	GO:0008201	heparin binding	Smoc2	IDA		Mouse	PMID:18757743
Molecular Function	GO:0005515	protein binding	SMOC2	IPI	UniProtKB:Q6L8H4	Human	PMID:32296183
Cellular Component	GO:0005604	basement membrane	Smoc2	IDA		Mouse	PMID:18757743
Cellular Component	GO:0071944	cell periphery	SMOC2	IDA		Human	PMID:16774925
Cellular Component	GO:0031012	extracellular matrix	Smoc2	IDA		Mouse	PMID:18757743
Cellular Component	GO:0005615	extracellular space	SMOC2	IDA		Human	PMID:16774925
Cellular Component	GO:0005614	interstitial matrix	Smoc2	IDA		Mouse	PMID:18757743
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	smoc2	IMP	ZFIN:ZDB-MRPHLNO-130726-5	Zfish	PMID:23559552
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	smoc2	IMP	ZFIN:ZDB-MRPHLNO-130726-4	Zfish	PMID:23559552
Biological Process	GO:0030198	extracellular matrix organization	Smoc2	IDA		Mouse	PMID:18757743
Biological Process	GO:0061515	myeloid cell development	smoc2	IMP	ZFIN:ZDB-MRPHLNO-150128-1	Zfish	PMID:25044883
Biological Process	GO:0042476	odontogenesis	smoc2	IMP	ZFIN:ZDB-MRPHLNO-120120-2	Zfish	PMID:22152679
Biological Process	GO:0042476	odontogenesis	smoc2	IMP	ZFIN:ZDB-MRPHLNO-120120-3	Zfish	PMID:22152679
Biological Process	GO:0045766	positive regulation of angiogenesis	SMOC2	IDA		Human	PMID:16774925
Biological Process	GO:0045766	positive regulation of angiogenesis	SMOC2	IGI	UniProtKB:P09038	Human	PMID:16774925
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	Smoc2	IDA		Mouse	PMID:18757743
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	SMOC2	IDA		Human	PMID:16774925
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	SMOC2	IGI	UniProtKB:P09038	Human	PMID:16774925
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	SMOC2	IGI	UniProtKB:P15692-4	Human	PMID:16774925
Biological Process	GO:2001028	positive regulation of endothelial cell chemotaxis	SMOC2	IGI	UniProtKB:P09038	Human	PMID:16774925
Biological Process	GO:0010595	positive regulation of endothelial cell migration	SMOC2	IDA		Human	PMID:16774925
Biological Process	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	SMOC2	IDA		Human	PMID:16774925
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	SMOC2	IDA		Human	PMID:16774925
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	SMOC2	IDA		Human	PMID:16774925
Biological Process	GO:0035470	positive regulation of vascular wound healing	SMOC2	IDA		Human	PMID:16774925
Biological Process	GO:0030510	regulation of BMP signaling pathway	smoc2	IMP	ZFIN:ZDB-MRPHLNO-150128-1	Zfish	PMID:25044883

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern