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Smoc2
Gene Detail
Symbol

Name
ID
Smoc2
SPARC related modular calcium binding 2
MGI:1929881
Synonyms
1700056C05Rik, 5430426J21Rik, Smoc2l
Feature Type
protein coding gene
Genetic Map
Chromosome 17
8.95 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr17:14279506-14404790 bp, + strand
From NCBI annotation of GRCm38

  125285 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11150  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Gene Tree: Smoc2

Human
homologs
Human Homolog SMOC2, SPARC related modular calcium binding 2
NCBI Gene ID 64094
neXtProt AC  NX_Q9H3U7
Human Synonyms  bA270C4A.1, bA37D8.1, dJ421D16.1, DTDP1, MST117, MSTP117, MSTP140, SMAP2
Human Chr (Location)  6q27; chr6:168441151-168667994 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SMOC2
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
Interactions
Smoc2 interacts with 219 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (10 records)
Data Summary: Results (217)    Tissues (121)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 6
RNA in situ 169
RT-PCR 42
cDNA source data(65)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(69) cDNA(67) Primer pair(2)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000023886 (Evidence)
Entrez Gene64074 (Evidence)
UniGene30162
DFCITC1575569, TC1593584, TC1734282
DoTSDT.492503, DT.91343278, DT.97374542
NIA Mouse Gene IndexU017514
Consensus CDS ProjectCCDS37442.1
International Mouse Knockout Project StatusSmoc2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 64074 NCBI Gene Model | MGI Sequence Detail 125285 C57BL/6J ±  kb
transcript NM_022315 RefSeq | MGI Sequence Detail 2832 C57BL/6 
polypeptide Q8CD91 UniProt | EBI | MGI Sequence Detail 447 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(803 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
InterPro IPR002350 Kazal domain
InterPro IPR019577 SPARC/Testican, calcium-binding domain
InterPro IPR000716 Thyroglobulin type-1
Protein Ontology PR:000015290 SPARC-related modular calcium-binding protein 2
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:191534 Bloch-Zupan A, et al., Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects. Am J Hum Genet. 2011 Dec 9;89(6):773-81
All references(46)
Other
accession IDs
MGI:1918668, MGI:1920709, MGI:1935165

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory