Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMCHD1
  • Mouse genes Smchd1
  • Rat genes Smchd1
  • Zfish genes smchd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smchd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	Smchd1	IDA		Mouse	MGI:MGI:5803776|PMID:26391951
Molecular Function	GO:0016887	ATP hydrolysis activity	Smchd1	IDA		Mouse	MGI:MGI:5902670|PMID:27059856
Molecular Function	GO:0005515	protein binding	SMCHD1	IPI	UniProtKB:Q5T3J3	Human	PMID:23542155
Molecular Function	GO:0005515	protein binding	SMCHD1	IPI	UniProtKB:Q5T3J3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	Smchd1	IPI	UniProtKB:Q8CDD9	Mouse	MGI:MGI:5803776|PMID:26391951
Molecular Function	GO:0042803	protein homodimerization activity	Smchd1	IDA		Mouse	MGI:MGI:5803776|PMID:26391951
Cellular Component	GO:0001740	Barr body	SMCHD1	IDA		Human	PMID:23542155
Cellular Component	GO:0001740	Barr body	Smchd1	IDA		Mouse	MGI:MGI:5803776|PMID:26391951
Cellular Component	GO:0001740	Barr body	Smchd1	IDA		Mouse	PMID:18425126
Cellular Component	GO:0000781	chromosome, telomeric region	SMCHD1	IDA		Human	PMID:24270157
Cellular Component	GO:0035861	site of double-strand break	SMCHD1	IDA		Human	PMID:24790221
Cellular Component	GO:0035861	site of double-strand break	SMCHD1	IDA		Human	PMID:25294876
Biological Process	GO:0060216	definitive hemopoiesis	smchd1	IMP	ZFIN:ZDB-MRPHLNO-170322-5	Zfish	PMID:31042481
Biological Process	GO:0009048	dosage compensation by inactivation of X chromosome	SMCHD1	IDA		Human	PMID:23542155
Biological Process	GO:0009048	dosage compensation by inactivation of X chromosome	Smchd1	IMP	MGI:MGI:3586547	Mouse	PMID:18425126
Biological Process	GO:0009048	dosage compensation by inactivation of X chromosome	Smchd1	IMP	MGI:MGI:3586547	Mouse	PMID:23754746
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	smchd1	IMP	ZFIN:ZDB-CRISPR-170322-1	Zfish	PMID:28067909
Biological Process	GO:0060820	inactivation of X chromosome by heterochromatin formation	Smchd1	IMP		Mouse	MGI:MGI:5532809|PMID:23754746
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	SMCHD1	IMP		Human	PMID:25294876
Biological Process	GO:0043584	nose development	SMCHD1	IMP		Human	PMID:28067909
Biological Process	GO:0043584	nose development	SMCHD1	IMP		Human	PMID:28067911
Biological Process	GO:0045739	positive regulation of DNA repair	SMCHD1	IMP		Human	PMID:24790221
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	SMCHD1	IMP		Human	PMID:25294876

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern