Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMARCA2
  • Mouse genes Smarca2
  • Rat genes Smarca2
  • Zfish genes smarca2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smarca2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Smarca2	IDA		Rat	PMID:15574597|RGD:9586065
Molecular Function	GO:0003682	chromatin binding	Smarca2	IDA		Rat	PMID:16452305|RGD:9586344
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:P35232	Human	PMID:12065415
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:O14497	Human	PMID:12200431
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:Q8NFD5	Human	PMID:12200431
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:P49715	Human	PMID:15107404
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:P51608	Human	PMID:15696166
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:Q07666	Human	PMID:16341228
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:P04326	Human	PMID:16601680
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:Q13127	Human	PMID:17984088
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:P28033	Human	PMID:20111005
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:Q8TAQ2	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:Q9NRD5	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:O00560	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:Q03468	Human	PMID:26030138
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:O00560	Human	PMID:26787460
Molecular Function	GO:0005515	protein binding	SMARCA2	IPI	UniProtKB:O14497	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	Smarca2	IPI	UniProtKB:Q9D8M7	Mouse	MGI:MGI:3775125|PMID:17640523
Molecular Function	GO:0005515	protein binding	Smarca2	IPI	UniProtKB:P53566	Mouse	MGI:MGI:5619486|PMID:15107404
Molecular Function	GO:0005515	protein binding	Smarca2	IPI	PR:Q99MR0	Mouse	PMID:12437990
Molecular Function	GO:0005515	protein binding	Smarca2	IPI	PR:Q9WTN3	Mouse	PMID:17074803
Molecular Function	GO:0005515	protein binding	Smarca2	IPI	PR:Q99MR0	Mouse	PMID:12368262
Molecular Function	GO:0000976	transcription cis-regulatory region binding	SMARCA2	IDA		Human	PMID:17984088
Molecular Function	GO:0003713	transcription coactivator activity	SMARCA2	IDA		Human	PMID:17984088
Cellular Component	GO:0000785	chromatin	SMARCA2	IDA		Human	PMID:12065415
Cellular Component	GO:0045111	intermediate filament cytoskeleton	SMARCA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SMARCA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0071565	nBAF complex	Smarca2	IDA		Mouse	MGI:MGI:3775125|PMID:17640523
Cellular Component	GO:0071565	nBAF complex	Smarca2	IDA		Mouse	PMID:23785148
Cellular Component	GO:0071564	npBAF complex	Smarca2	IDA		Mouse	MGI:MGI:3775125|PMID:17640523
Cellular Component	GO:0071564	npBAF complex	Smarca2	IDA		Mouse	PMID:23785148
Cellular Component	GO:0005654	nucleoplasm	SMARCA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SMARCA2	IDA		Human	PMID:17984088
Cellular Component	GO:0005634	nucleus	SMARCA2	IDA		Human	PMID:25593309
Cellular Component	GO:0005634	nucleus	Smarca2	IDA		Mouse	PMID:24137001
Cellular Component	GO:0005634	nucleus	Smarca2	IDA		Mouse	PMID:9603422
Cellular Component	GO:0016514	SWI/SNF complex	SMARCA2	IDA		Human	PMID:11078522
Cellular Component	GO:0070603	SWI/SNF superfamily-type complex	Smarca2	IDA		Mouse	PMID:12368262
Cellular Component	GO:0070603	SWI/SNF superfamily-type complex	Smarca2	IDA		Mouse	PMID:24335282
Biological Process	GO:0035887	aortic smooth muscle cell differentiation	Smarca2	IMP		Mouse	PMID:19342595
Biological Process	GO:0008283	cell population proliferation	Smarca2	IMP	MGI:MGI:2387988	Mouse	PMID:9843504
Biological Process	GO:0048144	fibroblast proliferation	Smarca2	IMP	MGI:MGI:2387988	Mouse	PMID:9843504
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	Smarca2	IMP		Mouse	PMID:26880577
Biological Process	GO:0031507	heterochromatin formation	smarca2	IMP	ZFIN:ZDB-MRPHLNO-191114-6	Zfish	PMID:30948728
Biological Process	GO:0031507	heterochromatin formation	smarca2	IMP	ZFIN:ZDB-MRPHLNO-141205-14	Zfish	PMID:30948728
Biological Process	GO:0030308	negative regulation of cell growth	SMARCA2	IMP		Human	PMID:12065415
Biological Process	GO:0008285	negative regulation of cell population proliferation	SMARCA2	IDA		Human	PMID:14660596
Biological Process	GO:0008285	negative regulation of cell population proliferation	Smarca2	IMP	MGI:MGI:2387988	Mouse	PMID:9843504
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	SMARCA2	IDA		Human	PMID:12065415
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	Smarca2	IMP	MGI:MGI:2387988	Mouse	PMID:9843504
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMARCA2	IDA		Human	PMID:17984088
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMARCA2	IMP		Human	PMID:8208605
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SMARCA2	IDA		Human	PMID:15774904
Biological Process	GO:0007286	spermatid development	Smarca2	IEP		Rat	PMID:22215678|RGD:9586361

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern