Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLF1
  • Mouse genes Slf1
  • Rat genes Slf1
  • Zfish genes slf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SLF1	IPI	UniProtKB:Q8IX21	Human	PMID:25931565
Molecular Function	GO:0005515	protein binding	Slf1	IPI	UniProtKB:Q9NS91	Mouse	PMID:15632077
Molecular Function	GO:0044877	protein-containing complex binding	SLF1	IPI	UniProtKB:Q96SB8	Human	PMID:25931565
Molecular Function	GO:0031625	ubiquitin protein ligase binding	SLF1	IPI	UniProtKB:Q9NS91	Human	PMID:25931565
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Slf1	IPI	UniProtKB:Q9NS91	Mouse	MGI:MGI:5688834|PMID:22036607
Cellular Component	GO:0005813	centrosome	Slf1	IDA		Mouse	PMID:15632077
Cellular Component	GO:0005737	cytoplasm	Slf1	IDA		Mouse	MGI:MGI:3528541|PMID:15632077
Cellular Component	GO:0042405	nuclear inclusion body	Slf1	IDA		Mouse	MGI:MGI:5688834|PMID:22036607
Cellular Component	GO:0005654	nucleoplasm	SLF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000786	nucleosome	Slf1	IDA		Mouse	MGI:MGI:3528541|PMID:15632077
Cellular Component	GO:0005634	nucleus	Slf1	IDA		Mouse	MGI:MGI:5688834|PMID:22036607
Cellular Component	GO:0005634	nucleus	Slf1	IDA		Mouse	PMID:15632077
Cellular Component	GO:0035861	site of double-strand break	SLF1	IDA		Human	PMID:25931565
Biological Process	GO:0006974	DNA damage response	SLF1	IDA		Human	PMID:25931565
Biological Process	GO:0006974	DNA damage response	Slf1	IDA		Mouse	MGI:MGI:5688834|PMID:22036607
Biological Process	GO:2000781	positive regulation of double-strand break repair	SLF1	IDA		Human	PMID:25931565
Biological Process	GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion	SLF1	IMP		Human	PMID:25931565
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	SLF1	IMP		Human	PMID:25931565
Biological Process	GO:1990166	protein localization to site of double-strand break	SLF1	IDA		Human	PMID:25931565

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern