Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC9A8
  • Mouse genes Slc9a8
  • Rat genes Slc9a8
  • Zfish genes slc9a8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc9a8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015386	potassium:proton antiporter activity	SLC9A8	IDA		Human	PMID:15522866
Molecular Function	GO:0005515	protein binding	SLC9A8	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0015385	sodium:proton antiporter activity	SLC9A8	IDA		Human	PMID:15522866
Molecular Function	GO:0015385	sodium:proton antiporter activity	Slc9a8	IDA		Rat	PMID:18209477|RGD:155663541
Molecular Function	GO:0015385	sodium:proton antiporter activity	Slc9a8	IDA		Rat	PMID:22088432|RGD:155663543
Cellular Component	GO:0001669	acrosomal vesicle	Slc9a8	IDA		Mouse	MGI:MGI:5918112|PMID:28476888
Cellular Component	GO:0016324	apical plasma membrane	SLC9A8	IDA		Human	PMID:34288721
Cellular Component	GO:0016324	apical plasma membrane	Slc9a8	IDA		Mouse	MGI:MGI:5474915|PMID:23220221
Cellular Component	GO:0016324	apical plasma membrane	Slc9a8	IDA		Rat	PMID:15731506|RGD:155663548
Cellular Component	GO:0016324	apical plasma membrane	Slc9a8	IDA		Rat	PMID:22088432|RGD:155663543
Cellular Component	GO:0000139	Golgi membrane	SLC9A8	IDA		Human	PMID:15522866
Cellular Component	GO:0032585	multivesicular body membrane	SLC9A8	IDA		Human	PMID:20719963
Cellular Component	GO:0032588	trans-Golgi network membrane	SLC9A8	IDA		Human	PMID:15522866
Cellular Component	GO:0032588	trans-Golgi network membrane	SLC9A8	IDA		Human	PMID:20719963
Biological Process	GO:0001675	acrosome assembly	Slc9a8	IMP		Mouse	MGI:MGI:5918112|PMID:28476888
Biological Process	GO:1902600	proton transmembrane transport	SLC9A8	IDA		Human	PMID:15522866
Biological Process	GO:1902600	proton transmembrane transport	Slc9a8	IDA		Rat	PMID:18209477|RGD:155663541
Biological Process	GO:1905526	regulation of Golgi lumen acidification	SLC9A8	IDA		Human	PMID:15522866
Biological Process	GO:0051453	regulation of intracellular pH	SLC9A8	IMP		Human	PMID:34288721
Biological Process	GO:0051453	regulation of intracellular pH	Slc9a8	IDA		Mouse	MGI:MGI:6844626|PMID:29958869
Biological Process	GO:0051453	regulation of intracellular pH	Slc9a8	IDA		Rat	PMID:22088432|RGD:155663543
Biological Process	GO:0035725	sodium ion transmembrane transport	SLC9A8	IDA		Human	PMID:15522866
Biological Process	GO:0035725	sodium ion transmembrane transport	Slc9a8	IDA		Rat	PMID:18209477|RGD:155663541

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern