Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC4A5
  • Mouse genes Slc4a5
  • Rat genes Slc4a5
  • Zfish genes slc4a5a,slc4a5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc4a5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008510	sodium:bicarbonate symporter activity	SLC4A5	IDA		Human	PMID:26447209
Molecular Function	GO:0008510	sodium:bicarbonate symporter activity	Slc4a5	IDA		Mouse	MGI:MGI:7327225|PMID:18588858
Cellular Component	GO:0016324	apical plasma membrane	SLC4A5	IDA		Human	PMID:26447209
Cellular Component	GO:0016324	apical plasma membrane	SLC4A5	IDA		Human	PMID:17715183
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a5	IDA		Rat	PMID:15151908|RGD:1303995
Biological Process	GO:0033326	cerebrospinal fluid secretion	Slc4a5	IMP		Mouse	PMID:21705333
Biological Process	GO:0002064	epithelial cell development	Slc4a5	IMP		Mouse	PMID:21705333
Biological Process	GO:0048311	mitochondrion distribution	Slc4a5	IMP		Mouse	PMID:21705333
Biological Process	GO:0006811	monoatomic ion transport	Slc4a5	IMP		Mouse	PMID:21705333
Biological Process	GO:0010468	regulation of gene expression	Slc4a5	IMP	MGI:MGI:5306980	Mouse	PMID:22082831
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	Slc4a5	IMP	MGI:MGI:5306980	Mouse	PMID:22082831
Biological Process	GO:0003014	renal system process	Slc4a5	IMP	MGI:MGI:5306980	Mouse	PMID:22082831
Biological Process	GO:0060041	retina development in camera-type eye	Slc4a5	IMP		Mouse	PMID:21705333

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern