Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC39A6
  • Mouse genes Slc39a6
  • Rat genes Slc39a6
  • Zfish genes slc39a6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc39a6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SLC39A6	IPI	UniProtKB:Q9ULF5	Human	PMID:27274087
Molecular Function	GO:0005515	protein binding	Slc39a6	IPI	UniProtKB:Q6P5F6	Mouse	MGI:MGI:5919849|PMID:27274087
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	SLC39A6	IDA		Human	PMID:15642354
Cellular Component	GO:0009986	cell surface	SLC39A6	HDA		Human	PMID:19581412
Cellular Component	GO:0005783	endoplasmic reticulum	Slc39a6	IDA		Mouse	PMID:11891044
Cellular Component	GO:0031258	lamellipodium membrane	SLC39A6	IDA		Human	PMID:12839489
Cellular Component	GO:0005886	plasma membrane	SLC39A6	IDA		Human	PMID:12839489
Cellular Component	GO:0005886	plasma membrane	SLC39A6	IDA		Human	PMID:15642354
Biological Process	GO:0042074	cell migration involved in gastrulation	slc39a6	IMP		Zfish	PMID:15129296
Biological Process	GO:0001837	epithelial to mesenchymal transition	slc39a6	IMP		Zfish	PMID:15129296
Biological Process	GO:0006882	intracellular zinc ion homeostasis	SLC39A6	IDA		Human	PMID:15642354
Biological Process	GO:0006882	intracellular zinc ion homeostasis	slc39a6	IMP	ZFIN:ZDB-GENO-210831-16	Zfish	PMID:30851936
Biological Process	GO:0033077	T cell differentiation in thymus	slc39a6	IMP	ZFIN:ZDB-GENO-210831-16	Zfish	PMID:30851936
Biological Process	GO:0071578	zinc ion import across plasma membrane	SLC39A6	IDA		Human	PMID:15642354
Biological Process	GO:0071577	zinc ion transmembrane transport	SLC39A6	IMP		Human	PMID:12839489

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern