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Slc39a6 Gene Detail
Summary
  • Symbol
    Slc39a6
  • Name
    solute carrier family 39 (metal ion transporter), member 6
  • Synonyms
    Ermelin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147279
    NCBI Gene: 106957
  • Gene Overview
    MyGene.info: SLC39A6
Location & Maps
more
  • Sequence Map
    Chr18:24579881-24603817 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23937 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 13.18 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC39A6, solute carrier family 39 member 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC39A6, solute carrier family 39 member 6
    Orthology source: HGNC, HomoloGene
  • Synonyms
    LIV-1, ZIP6
  • Links
    NCBI Gene ID: 25800
    neXtProt AC: NX_Q13433

  • Chr Location
    18q12.2; chr18:36108531-36129814 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    11
  • Gene trapped
    5
  • Targeted
    6
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033982 VEGA Gene Model | MGI Sequence Detail 23937 C57BL/6J ±  kb
transcript OTTMUST00000085755 VEGA | MGI Sequence Detail 3882 Not Applicable  
polypeptide OTTMUSP00000046356 VEGA | MGI Sequence Detail 765 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    94 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015133 zinc transporter ZIP6
  • InterPro Domains
    IPR003689 Zinc/iron permease
Molecular
Reagents
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  • All nucleic 79
    cDNA 78
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:75677 Suzuki A, et al., Ermelin, an endoplasmic reticulum transmembrane protein, contains the novel HELP domain conserved in eukaryotes. Gene. 2002 Feb 6;284(1-2):31-40
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory