Slc39a6
Gene Detail

Symbol

Name
ID

Slc39a6
solute carrier family 39 (metal ion transporter), member 6
MGI:2147279

Synonyms

Ermelin

Feature Type

protein coding gene

Genetic Map

Chromosome 18
13.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr18:24579881-24603817 bp, - strand From VEGA annotation of GRCm38   23937 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:8199  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc39a6

Human
homologs

Human Homolog		SLC39A6, solute carrier family 39 (zinc transporter), member 6
NCBI Gene ID		25800
neXtProt AC		NX_Q13433
Human Synonyms		LIV-1
Human Chr (Location)		18q12.2; chr18:36108531-36129394 (-)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(11) : Gene trapped(5) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Slc39a6 interacts with 182 markers (Mir7-1, Mir9-1, Mir9-2, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (19 annotations)

Process	cellular zinc ion homeostasis, divalent inorganic cation transport, ...
Component	cell surface, endoplasmic reticulum, ...
Function	metal ion transmembrane transporter activity, zinc ion transmembrane transporter activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)

Data Summary: Results (4)    Tissues (4)    Images (1)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	4

cDNA source data(78)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas

Molecular
reagents

All nucleic(79) cDNA(78) Primer pair(1)
Microarray probesets(4)

Other database
links

VEGA Gene Model	OTTMUSG00000033982 (Evidence)
Ensembl Gene Model	ENSMUSG00000024270 (Evidence)
Entrez Gene	106957 (Evidence)
UniGene	21688
DFCI	TC1577239
DoTS	DT.101183203, DT.489387
Consensus CDS Project	CCDS50239.1
International Mouse Knockout Project Status	Slc39a6

Sequences

Length	Strain/Species
genomic	OTTMUSG00000033982	VEGA Gene Model | MGI Sequence Detail	23937	C57BL/6J
transcript	OTTMUST00000085755	VEGA | MGI Sequence Detail	3882	Not Applicable
polypeptide	OTTMUSP00000046356	VEGA | MGI Sequence Detail	765	Not Applicable

All sequences(36) RefSeq(2) UniProt(5)

Polymorphisms

SNPs within 2kb(95 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR003689	Zinc/iron permease
Protein Ontology	PR:000015133	zinc transporter ZIP6

References

(Earliest) J:75677 Suzuki A, et al., Ermelin, an endoplasmic reticulum transmembrane protein, contains the novel HELP domain conserved in eukaryotes. Gene. 2002 Feb 6;284(1-2):31-40
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)