Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC39A4
  • Mouse genes Slc39a4
  • Rat genes Slc39a4
  • Zfish genes slc39a4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc39a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SLC39A4	IDA		Human	PMID:30874431
Molecular Function	GO:0046872	metal ion binding	SLC39A4	IMP		Human	PMID:25882556
Molecular Function	GO:0046872	metal ion binding	SLC39A4	EXP		Human	PMID:30793391
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	SLC39A4	IDA		Human	PMID:22242765
Cellular Component	GO:0016324	apical plasma membrane	Slc39a4	IDA		Mouse	MGI:MGI:3831211|PMID:18936158
Cellular Component	GO:0016324	apical plasma membrane	Slc39a4	IDA		Mouse	PMID:15358787
Cellular Component	GO:0031410	cytoplasmic vesicle	SLC39A4	IDA		Human	PMID:14612438
Cellular Component	GO:0005886	plasma membrane	SLC39A4	IDA		Human	PMID:14612438
Cellular Component	GO:0005886	plasma membrane	SLC39A4	IDA		Human	PMID:30874431
Cellular Component	GO:0005886	plasma membrane	SLC39A4	IDA		Human	PMID:31164399
Biological Process	GO:0034224	cellular response to zinc ion starvation	Slc39a4	IDA		Mouse	PMID:15358787
Biological Process	GO:0051238	sequestering of metal ion	SLC39A4	IMP		Human	PMID:25882556
Biological Process	GO:0051238	sequestering of metal ion	SLC39A4	EXP		Human	PMID:30793391

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern