Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC30A10
  • Mouse genes Slc30a10
  • Rat genes Slc30a10
  • Zfish genes slc30a10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc30a10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015368	calcium:monoatomic cation antiporter activity	SLC30A10	IDA		Human	PMID:30755481
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	SLC30A10	IDA		Human	PMID:25319704
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	SLC30A10	IMP		Human	PMID:27226609
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	SLC30A10	IMP		Human	PMID:27307044
Molecular Function	GO:0005515	protein binding	SLC30A10	IPI	UniProtKB:O14863	Human	PMID:26728129
Molecular Function	GO:0005515	protein binding	SLC30A10	IPI	UniProtKB:Q99726	Human	PMID:26728129
Molecular Function	GO:0005515	protein binding	SLC30A10	IPI	UniProtKB:Q9BRI3	Human	PMID:26728129
Molecular Function	GO:0005515	protein binding	Slc30a10	IPI	UniProtKB:Q2HJ10	Mouse	MGI:MGI:5897529|PMID:26728129
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	SLC30A10	IDA		Human	PMID:22427991
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	SLC30A10	IDA		Human	PMID:26728129
Cellular Component	GO:0005769	early endosome	SLC30A10	IDA		Human	PMID:26728129
Cellular Component	GO:0031901	early endosome membrane	SLC30A10	IDA		Human	PMID:22427991
Cellular Component	GO:0005794	Golgi apparatus	SLC30A10	IDA		Human	PMID:22706290
Cellular Component	GO:0005794	Golgi apparatus	SLC30A10	IDA		Human	PMID:27226609
Cellular Component	GO:0005886	plasma membrane	SLC30A10	IDA		Human	PMID:25319704
Cellular Component	GO:0005886	plasma membrane	SLC30A10	IDA		Human	PMID:27226609
Cellular Component	GO:0005886	plasma membrane	SLC30A10	IDA		Human	PMID:27307044
Cellular Component	GO:0055037	recycling endosome	SLC30A10	IDA		Human	PMID:26728129
Cellular Component	GO:0055038	recycling endosome membrane	SLC30A10	IDA		Human	PMID:22427991
Biological Process	GO:1904385	cellular response to angiotensin	SLC30A10	IDA		Human	PMID:22427991
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	SLC30A10	IDA		Human	PMID:26728129
Biological Process	GO:0030026	intracellular manganese ion homeostasis	SLC30A10	IMP		Human	PMID:22341972
Biological Process	GO:0030026	intracellular manganese ion homeostasis	SLC30A10	IDA		Human	PMID:25319704
Biological Process	GO:0030026	intracellular manganese ion homeostasis	SLC30A10	IMP		Human	PMID:27226609
Biological Process	GO:0030026	intracellular manganese ion homeostasis	SLC30A10	IMP		Human	PMID:27307044
Biological Process	GO:0006882	intracellular zinc ion homeostasis	SLC30A10	IDA		Human	PMID:22427991
Biological Process	GO:0006882	intracellular zinc ion homeostasis	SLC30A10	IDA		Human	PMID:26728129
Biological Process	GO:0140048	manganese ion export across plasma membrane	SLC30A10	IDA		Human	PMID:25319704
Biological Process	GO:0140048	manganese ion export across plasma membrane	SLC30A10	IMP		Human	PMID:27307044
Biological Process	GO:0055071	manganese ion homeostasis	Slc30a10	IMP		Mouse	MGI:MGI:5909356|PMID:28461334
Biological Process	GO:0055071	manganese ion homeostasis	slc30a10	IMP	ZFIN:ZDB-GENO-171020-2	Zfish	PMID:28692648
Biological Process	GO:0006828	manganese ion transport	SLC30A10	IMP		Human	PMID:22341972
Biological Process	GO:0006828	manganese ion transport	SLC30A10	IMP		Human	PMID:26728129
Biological Process	GO:0006828	manganese ion transport	slc30a10	IMP	ZFIN:ZDB-GENO-171020-2	Zfish	PMID:28692648
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	SLC30A10	IDA		Human	PMID:26728129
Biological Process	GO:0062111	zinc ion import into organelle	SLC30A10	IDA		Human	PMID:22427991

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern