Slc30a10 MGI Mouse Gene Detail - MGI:2685058 - solute carrier family 30, member 10

Slc30a10 Gene Detail

Symbol

Slc30a10
Name

solute carrier family 30, member 10
Synonyms

E130106K10Rik

Feature Type

protein coding gene
IDs

MGI:2685058
NCBI Gene: 226781

Sequence Map

Chr1:185454848-185468762 bp, + strand
From NCBI annotation of GRCm38

Mouse Genome Browser
Download
Sequence

13915 bp ± kb flank
Genome Browsers

VEGA | Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 89.53 cM
Mapping Data

2 experiments

Human Ortholog

SLC30A10, solute carrier family 30 member 10

Vertebrate Orthologs

9

Human Ortholog

SLC30A10, solute carrier family 30 member 10
Orthology source: HomoloGene, HGNC
Synonyms

HMDPC, HMNDYT1, ZnT-10, ZNT10, ZNT8, ZRC1
Links

HGNC:25355

NCBI Gene ID: 55532

neXtProt AC: NX_Q6XR72
Chr Location

1q41; chr1:219913919-219959315 (-) GRCh38.p2

HomoloGene

Vertebrate Homology Class 100946
1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed
HCOP

human homology predictions: SLC30A10
Protein SuperFamily

cation efflux protein
Gene Tree

Slc30a10

Diseases

1 with human SLC30A10 associations

				Human Disease	Mouse Models
				Hypermanganesemia with Dystonia 1; HMNDYT1 OMIM: 613280

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

2 phenotype references

All Mutations and Alleles

2
Targeted

2
Incidental Mutations

Mutagenetix , APF

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All GO Annotations

14
GO References

4

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	receptor	receptor binding	RNA binding	transcription	transferase	transporter

Biological Process

nucleic acid-templated transcription	carbohydrate derivative metabolism	cell death	cell differentiation	cell proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

29
Tissues

29
cDNA Data

25
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO
Other Vertebrate Links

Xenbase slc30a10

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Slc30a10 interacts with 388 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

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All Sequences

19
RefSeq

2
UniProt

1
CCDS

CCDS15599.1
UniGene

227117

Ensembl

ENSMUSG00000026614 (Evidence)
NCBI Gene

226781

			Length	Strain/Species	Flank
genomic	226781	NCBI Gene Model \| MGI Sequence Detail	13915	C57BL/6J	± kb
transcript	NM_001033286	RefSeq \| MGI Sequence Detail	5836	C57BL/6
polypeptide	Q3UVU3	UniProt \| EBI \| MGI Sequence Detail	470	Not Applicable

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SNPs within 2kb

212 from dbSNP Build 142

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UniProt

1 Sequence
Protein Ontology

PR:000015074 zinc transporter 10
InterPro Domains

IPR002524 Cation efflux protein

IPR027469 Cation efflux protein transmembrane domain

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All nucleic 27

cDNA 25

Primer pair 1

Other 1

Microarray probesets 4

Summaries

All 25

Developmental Gene Expression 1

Gene Ontology 4

Phenotypes 2
Earliest

J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
Latest

J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 09/13/2016 MGI 6.05