Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC2A10
  • Mouse genes Slc2a10
  • Rat genes Slc2a10
  • Zfish genes slc2a10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc2a10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0055056	D-glucose transmembrane transporter activity	SLC2A10	IDA		Human	PMID:11592815
Molecular Function	GO:0033300	dehydroascorbic acid transmembrane transporter activity	SLC2A10	IDA		Human	PMID:27153185
Cellular Component	GO:0005829	cytosol	SLC2A10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	SLC2A10	IDA		Human	PMID:16550171
Cellular Component	GO:0005886	plasma membrane	SLC2A10	IDA		Human	PMID:11592815
Biological Process	GO:0060840	artery development	SLC2A10	IMP		Human	PMID:16550171
Biological Process	GO:0060840	artery development	SLC2A10	IMP		Human	PMID:18565096
Biological Process	GO:0045454	cell redox homeostasis	SLC2A10	IMP		Human	PMID:26376865
Biological Process	GO:0072359	circulatory system development	slc2a10	IMP	ZFIN:ZDB-MRPHLNO-120319-6	Zfish	PMID:22116938
Biological Process	GO:0072359	circulatory system development	slc2a10	IMP	ZFIN:ZDB-MRPHLNO-120319-5	Zfish	PMID:22116938
Biological Process	GO:0070837	dehydroascorbic acid transport	SLC2A10	IDA		Human	PMID:27153185
Biological Process	GO:0072498	embryonic skeletal joint development	SLC2A10	IMP		Human	PMID:18565096
Biological Process	GO:0098708	glucose import across plasma membrane	SLC2A10	IDA		Human	PMID:11592815
Biological Process	GO:0032683	negative regulation of connective tissue growth factor production	SLC2A10	IMP		Human	PMID:16550171
Biological Process	GO:0032683	negative regulation of connective tissue growth factor production	SLC2A10	IMP		Human	PMID:26376865
Biological Process	GO:0010629	negative regulation of gene expression	SLC2A10	IMP		Human	PMID:16550171
Biological Process	GO:2001045	negative regulation of integrin-mediated signaling pathway	SLC2A10	IMP		Human	PMID:26376865
Biological Process	GO:1902729	negative regulation of proteoglycan biosynthetic process	SLC2A10	IMP		Human	PMID:16550171
Biological Process	GO:0060392	negative regulation of SMAD protein signal transduction	SLC2A10	IMP		Human	PMID:16550171
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	SLC2A10	IMP		Human	PMID:16550171
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	SLC2A10	IMP		Human	PMID:26376865
Biological Process	GO:0030903	notochord development	slc2a10	IMP	ZFIN:ZDB-MRPHLNO-120319-6	Zfish	PMID:22116938
Biological Process	GO:0030903	notochord development	slc2a10	IMP	ZFIN:ZDB-MRPHLNO-120319-5	Zfish	PMID:22116938
Biological Process	GO:0010628	positive regulation of gene expression	SLC2A10	IMP		Human	PMID:16550171
Biological Process	GO:1902730	positive regulation of proteoglycan biosynthetic process	SLC2A10	IMP		Human	PMID:16550171
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	SLC2A10	IMP		Human	PMID:26376865
Biological Process	GO:1903053	regulation of extracellular matrix organization	SLC2A10	IMP		Human	PMID:26376865
Biological Process	GO:0043588	skin development	SLC2A10	IMP		Human	PMID:18565096

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern