Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC24A5
  • Mouse genes Slc24a5
  • Rat genes Slc24a5
  • Zfish genes slc24a5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc24a5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015085	calcium ion transmembrane transporter activity	Slc24a5	IDA		Mouse	MGI:MGI:6718234|PMID:27093457
Molecular Function	GO:0008273	calcium, potassium:sodium antiporter activity	SLC24A5	IDA		Human	PMID:18166528
Molecular Function	GO:0008273	calcium, potassium:sodium antiporter activity	SLC24A5	IDA		Human	PMID:27093457
Molecular Function	GO:0005515	protein binding	SLC24A5	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Cellular Component	GO:0005802	trans-Golgi network	SLC24A5	IDA		Human	PMID:18166528
Biological Process	GO:0070509	calcium ion import	SLC24A5	IDA		Human	PMID:27093457
Biological Process	GO:0070509	calcium ion import	Slc24a5	IDA		Mouse	MGI:MGI:6718234|PMID:27093457
Biological Process	GO:0048066	developmental pigmentation	slc24a5	IMP	ZFIN:ZDB-GENO-120316-74	Zfish	PMID:9007256
Biological Process	GO:0048066	developmental pigmentation	slc24a5	IMP	ZFIN:ZDB-GENO-120316-73	Zfish	PMID:9007256
Biological Process	GO:0042438	melanin biosynthetic process	Slc24a5	IMP		Mouse	PMID:18166528
Biological Process	GO:0030318	melanocyte differentiation	slc24a5	IMP	ZFIN:ZDB-GENO-970801-17	Zfish	PMID:16357253
Biological Process	GO:0097324	melanocyte migration	slc24a5	IMP	ZFIN:ZDB-GENO-100708-1	Zfish	PMID:24173565
Biological Process	GO:0034220	monoatomic ion transmembrane transport	SLC24A5	IDA		Human	PMID:18166528
Biological Process	GO:0048022	negative regulation of melanin biosynthetic process	Slc24a5	IMP		Mouse	PMID:18166528
Biological Process	GO:0043473	pigmentation	slc24a5	IMP	ZFIN:ZDB-GENO-120316-74	Zfish	PMID:9007256
Biological Process	GO:0043473	pigmentation	slc24a5	IMP	ZFIN:ZDB-GENO-120316-73	Zfish	PMID:9007256

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern