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Slc24a5
Gene Detail
Symbol

Name
ID
Slc24a5
solute carrier family 24, member 5
MGI:2677271
Synonyms
F630045L20Rik, NCKX5, NCX5, Oca6
Feature Type
protein coding gene
Genetic Map
Chromosome 2
61.14 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:125068124-125088677 bp, + strand
From VEGA annotation of GRCm38

  20554 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18400  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC24A5
Gene Tree: Slc24a5

Human
homologs
SLC24A5, solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 283652
neXtProt AC: NX_Q71RS6

Human Synonyms: JSX, NCKX5, OCA6, SHEP4

Human Chr (Location): 15q21.1; chr15:48120972-48142392 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit hypopigmentation and ocular albinism.
 
Interactions
Slc24a5 interacts with 82 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (102)    Tissues (7)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 102
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc24a5 ; ZFIN slc24a5    NEW 
Molecular
reagents
All nucleic(24) cDNA(23) Primer pair(1)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000015345 (Evidence)
Ensembl Gene Model ENSMUSG00000035183 (Evidence)
Entrez Gene 317750 (Evidence)
UniGene 330538
DFCI TC1581506
DoTS DT.97389263
NIA Mouse Gene Index U002405
Consensus CDS Project CCDS38226.1
International Mouse Phenotyping Consortium Status Slc24a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015345 VEGA Gene Model | MGI Sequence Detail 20554 C57BL/6J ±  kb
transcript OTTMUST00000036369 VEGA | MGI Sequence Detail 1954 Not Applicable 
polypeptide OTTMUSP00000016349 VEGA | MGI Sequence Detail 501 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(164 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004837 Sodium/calcium exchanger membrane region
InterPro IPR004481 Sodium/potassium/calcium exchanger
Protein Ontology PR:000015002 sodium/potassium/calcium exchanger 5
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory