Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC16A3
  • Mouse genes Slc16a3
  • Rat genes Slc16a3
  • Zfish genes slc16a3a,slc16a3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc16a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015129	lactate transmembrane transporter activity	Slc16a3	IMP	MGI:MGI:6467009	Mouse	PMID:31837519
Molecular Function	GO:0015650	lactate:proton symporter activity	SLC16A3	IDA		Human	PMID:11101640
Molecular Function	GO:0015650	lactate:proton symporter activity	Slc16a3	IDA		Rat	PMID:10926847|RGD:152995558
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:P26453	Human	PMID:10921872
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:Q86WQ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:Q12959	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:P84074	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:Q8WUI4-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC16A3	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0050833	pyruvate transmembrane transporter activity	SLC16A3	IDA		Human	PMID:31719150
Molecular Function	GO:0003723	RNA binding	SLC16A3	HDA		Human	PMID:22658674
Cellular Component	GO:0016324	apical plasma membrane	SLC16A3	IDA		Human	PMID:31791063
Cellular Component	GO:0016323	basolateral plasma membrane	SLC16A3	IDA		Human	PMID:21199217
Cellular Component	GO:0016323	basolateral plasma membrane	SLC16A3	IDA		Human	PMID:31791063
Cellular Component	GO:0016328	lateral plasma membrane	SLC16A3	IDA		Human	PMID:26854723
Cellular Component	GO:0031965	nuclear membrane	SLC16A3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Slc16a3	IDA		Rat	PMID:11291733|RGD:13702356
Cellular Component	GO:0005886	plasma membrane	SLC16A3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SLC16A3	IDA		Human	PMID:10921872
Cellular Component	GO:0005886	plasma membrane	SLC16A3	IDA		Human	PMID:28112518
Cellular Component	GO:0005886	plasma membrane	Slc16a3	IDA		Mouse	PMID:18385447
Cellular Component	GO:0005886	plasma membrane	Slc16a3	IDA		Mouse	PMID:31837519
Cellular Component	GO:0005886	plasma membrane	Slc16a3	IDA		Rat	PMID:10921872|RGD:8553745
Cellular Component	GO:0005886	plasma membrane	Slc16a3	IDA		Rat	PMID:19929853|RGD:7327222
Cellular Component	GO:0098839	postsynaptic density membrane	Slc16a3	IDA		Rat	PMID:11291733|RGD:13702356
Cellular Component	GO:0045202	synapse	SLC16A3	IDA		Human	PMID:11101640
Biological Process	GO:0035873	lactate transmembrane transport	SLC16A3	IDA		Human	PMID:11101640
Biological Process	GO:0035879	plasma membrane lactate transport	Slc16a3	IDA		Rat	PMID:10926847|RGD:152995558
Biological Process	GO:0035879	plasma membrane lactate transport	Slc16a3	IDA		Rat	PMID:19929853|RGD:7327222
Biological Process	GO:0030163	protein catabolic process	SLC16A3	IDA		Human	PMID:11101640
Biological Process	GO:0042867	pyruvate catabolic process	Slc16a3	IMP	MGI:MGI:6467009	Mouse	PMID:31837519
Biological Process	GO:1901475	pyruvate transmembrane transport	SLC16A3	IDA		Human	PMID:31719150

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern