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Slc16a3
Gene Detail
Symbol

Name
ID
Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
MGI:1933438
Synonyms
MCT3, MCT4, monocarboxylate transporter 4
Feature Type
protein coding gene
Genetic Map
Chromosome 11
84.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:120948480-120958775 bp, + strand
From VEGA annotation of GRCm38

  10296 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37900  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: SLC16A3
Gene Tree: Slc16a3

Human
homologs
SLC16A3, solute carrier family 16 (monocarboxylate transporter), member 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 9123
neXtProt AC: NX_O15427

Human Synonyms: MCT3, MCT 3, MCT-3, MCT4, MCT 4, MCT-4

Human Chr (Location): 17q25; chr17:82228406-82239499 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(7) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Slc16a3 interacts with 267 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (162)    Tissues (131)    Images (37)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 156
RT-PCR 6
cDNA source data(84)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc16a3 ; ZFIN slc16a3    NEW 
Molecular
reagents
All nucleic(86) cDNA(84) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000004161 (Evidence)
Ensembl Gene Model ENSMUSG00000025161 (Evidence)
Entrez Gene 80879 (Evidence)
UniGene 28632
DFCI TC1578679
Consensus CDS Project CCDS25761.1
International Mouse Phenotyping Consortium Status Slc16a3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004161 VEGA Gene Model | MGI Sequence Detail 10296 C57BL/6J ±  kb
transcript OTTMUST00000009433 VEGA | MGI Sequence Detail 2272 Not Applicable 
polypeptide OTTMUSP00000004592 VEGA | MGI Sequence Detail 470 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(10) UniProt(5)
Polymorphisms
SNPs within 2kb(27 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011701 Major facilitator superfamily
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR004743 Monocarboxylate transporter
Protein Ontology PR:000014951 monocarboxylate transporter 4
References
(Earliest) J:76794 Herubel F, et al., Genetic expression of monocarboxylate transporters during human and murine oocyte maturation and early embryonic development. Zygote. 2002 May;10(2):175-81
(Latest) J:219917 Domenech-Estevez E, et al., Distribution of monocarboxylate transporters in the peripheral nervous system suggests putative roles in lactate shuttling and myelination. J Neurosci. 2015 Mar 11;35(10):4151-6
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory