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Slc16a3 Gene Detail
Summary
  • Symbol
    Slc16a3
  • Name
    solute carrier family 16 (monocarboxylic acid transporters), member 3
  • Synonyms
    MCT3, MCT4, monocarboxylate transporter 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933438
    NCBI Gene: 80879
  • Gene Overview
    MyGene.info: SLC16A3
Location & Maps
more
  • Sequence Map
    Chr11:120948480-120958775 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10296 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SLC16A3, solute carrier family 16 member 3
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SLC16A3, solute carrier family 16 member 3
    Orthology source: HomoloGene
  • Synonyms
    MCT3, MCT 3, MCT-3, MCT4, MCT 4, MCT-4
  • Links
    NCBI Gene ID: 9123
    neXtProt AC: NX_O15427

  • Chr Location
    17q25; chr17:82228406-82239499 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004161 VEGA Gene Model | MGI Sequence Detail 10296 C57BL/6J ±  kb
transcript OTTMUST00000009433 VEGA | MGI Sequence Detail 2272 Not Applicable  
polypeptide OTTMUSP00000004592 VEGA | MGI Sequence Detail 470 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    27 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000014951 monocarboxylate transporter 4
  • InterPro Domains
    IPR011701 Major facilitator superfamily
    IPR020846 Major facilitator superfamily domain
    IPR004743 Monocarboxylate transporter
    IPR030756 Monocarboxylate transporter 4
Molecular
Reagents
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  • All nucleic 86
    cDNA 84
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 39
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:76794 Herubel F, et al., Genetic expression of monocarboxylate transporters during human and murine oocyte maturation and early embryonic development. Zygote. 2002 May;10(2):175-81
  • Latest
    J:224040 Saraswati S, et al., Prolonged hypoxia induces monocarboxylate transporter-4 expression in mesenchymal stem cells resulting in a secretome that is deleterious to cardiovascular repair. Stem Cells. 2015 Apr;33(4):1333-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory