Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SHROOM4
  • Mouse genes Shroom4
  • Rat genes Shroom4
  • Zfish genes shroom4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Shroom4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Shroom4	IDA		Mouse	PMID:17009331
Molecular Function	GO:0045159	myosin II binding	Shroom4	IDA		Mouse	PMID:17009331
Cellular Component	GO:0015629	actin cytoskeleton	Shroom4	IDA		Mouse	PMID:17009331
Cellular Component	GO:0005884	actin filament	SHROOM4	IDA		Human	PMID:16249884
Cellular Component	GO:0005884	actin filament	SHROOM4	IDA		Human	PMID:16684770
Cellular Component	GO:0016324	apical plasma membrane	Shroom4	IDA		Mouse	PMID:17009331
Cellular Component	GO:0009925	basal plasma membrane	Shroom4	IDA		Mouse	PMID:17009331
Cellular Component	GO:0030864	cortical actin cytoskeleton	Shroom4	IDA		Mouse	MGI:MGI:3690292|PMID:16684770
Cellular Component	GO:0005737	cytoplasm	Shroom4	IDA		Mouse	PMID:17009331
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	SHROOM4	IDA		Human	PMID:16249884
Cellular Component	GO:0005925	focal adhesion	SHROOM4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SHROOM4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SHROOM4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001725	stress fiber	Shroom4	IDA		Mouse	PMID:17009331
Biological Process	GO:0007015	actin filament organization	Shroom4	IDA		Mouse	PMID:17009331
Biological Process	GO:0007420	brain development	SHROOM4	IDA		Human	PMID:16249884
Biological Process	GO:0050890	cognition	SHROOM4	IDA		Human	PMID:16249884

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern