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Shroom4
Gene Detail
 Symbol
Name
ID
Shroom4
shroom family member 4
MGI:2685570
Synonyms D430043L16Rik, Shrm4
Feature Type protein coding gene
Genetic Map
Chromosome X
2.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:6399854-6637448 bp, + strand
From VEGA annotation of GRCm38

  237595 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:26615  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Shroom4

Human
homologs
Human Homolog SHROOM4, shroom family member 4
NCBI Gene ID 57477
neXtProt AC  NX_Q9ULL8
Human Synonyms  SHAP
Human Chr (Location)  Xp11.22; chrX:50591642-50814044 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SHROOM4
Alleles
and
phenotypes
All alleles(2) : Targeted(1) Gene trapped(1)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process actin filament organization, brain development, ...
Component actin cytoskeleton, apical plasma membrane, ...
Function actin binding, actin filament binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (24)    Tissues (23)   
Theiler Stages: 11, 13, 15, 17, 19, 20, 21, 22, 23, 24, 28
Assay TypeResults
RT-PCR 24
cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(19) cDNA(18) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000016659 (Evidence)
Ensembl Gene ModelENSMUSG00000068270 (Evidence)
Entrez Gene208431 (Evidence)
UniGene23208
DFCITC1602455
DoTSDT.101288513, DT.55269914, DT.91587745
NIA Mouse Gene IndexU019694
Consensus CDS ProjectCCDS29959.1
International Mouse Knockout Project StatusShroom4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016659 VEGA Gene Model | MGI Sequence Detail 237595 C57BL/6J ±  kb
transcript OTTMUST00000040329 VEGA | MGI Sequence Detail 4839 Not Applicable 
polypeptide OTTMUSP00000051223 VEGA | MGI Sequence Detail 1475 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(409 from dbSNP Build 137)    SNPs within 2kb including multiple locations(415)
Protein-related
information
ResourceIDDescription
InterPro IPR014799 Apx/shroom, ASD2
InterPro IPR001478 PDZ domain
Protein Ontology PR:000014857 protein Shroom4
References (Earliest) J:114885 Dietz ML, et al., Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins. J Biol Chem. 2006 Jul 21;281(29):20542-54
(Latest) J:124995 Etournay R, et al., Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions. J Cell Sci. 2007 Aug 15;120(Pt 16):2838-50
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory