Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SHISA6
  • Mouse genes Shisa6
  • Rat genes Shisa6
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Shisa6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Shisa6	IDA		Mouse	MGI:MGI:5805758|PMID:26931375
Molecular Function	GO:0030165	PDZ domain binding	Shisa6	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:5805758|PMID:26931375
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:O76071	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:O95817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:P38936	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:P46934-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:P57075-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q15654	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q49AR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q58EX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q6DKK2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q8WUP2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q92993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q96PN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q99471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q9BYR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q9H6L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q9HAQ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SHISA6	IPI	UniProtKB:Q9NQT4	Human	PMID:32296183
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Shisa6	IDA		Mouse	PMID:22632720
Cellular Component	GO:0098985	asymmetric, glutamatergic, excitatory synapse	Shisa6	IDA		Mouse	MGI:MGI:5805758|PMID:26931375
Cellular Component	GO:0098978	glutamatergic synapse	Shisa6	IDA		Mouse	PMID:26931375
Cellular Component	GO:0098978	glutamatergic synapse	Shisa6	IMP		Mouse	PMID:26931375
Cellular Component	GO:0098978	glutamatergic synapse	Shisa6	IEP		Mouse	PMID:26931375
Cellular Component	GO:0098978	glutamatergic synapse	Shisa6	IPI		Mouse	PMID:26931375
Cellular Component	GO:0014069	postsynaptic density	Shisa6	IDA		Mouse	MGI:MGI:5805758|PMID:26931375
Cellular Component	GO:0098839	postsynaptic density membrane	Shisa6	IDA		Mouse	PMID:26931375
Cellular Component	GO:0098839	postsynaptic density membrane	Shisa6	IPI		Mouse	PMID:26931375
Cellular Component	GO:0098839	postsynaptic density membrane	Shisa6	IEP		Mouse	PMID:26931375
Cellular Component	GO:0098839	postsynaptic density membrane	Shisa6	IMP		Mouse	PMID:26931375
Biological Process	GO:0098976	excitatory chemical synaptic transmission	Shisa6	IMP		Mouse	MGI:MGI:5805758|PMID:26931375
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Shisa6	IMP		Mouse	MGI:MGI:6119909|PMID:28196692
Biological Process	GO:0098970	postsynaptic neurotransmitter receptor diffusion trapping	Shisa6	IDA		Mouse	PMID:26931375
Biological Process	GO:0098970	postsynaptic neurotransmitter receptor diffusion trapping	Shisa6	IMP		Mouse	PMID:26931375
Biological Process	GO:0098970	postsynaptic neurotransmitter receptor diffusion trapping	Shisa6	IPI		Mouse	PMID:26931375
Biological Process	GO:1904717	regulation of AMPA glutamate receptor clustering	Shisa6	IMP		Mouse	MGI:MGI:5805758|PMID:26931375
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	Shisa6	IDA		Mouse	PMID:26931375
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	Shisa6	IMP		Mouse	PMID:26931375
Biological Process	GO:0007283	spermatogenesis	Shisa6	IMP		Mouse	MGI:MGI:6119909|PMID:28196692

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern