Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SGSH
  • Mouse genes Sgsh
  • Rat genes
  • Zfish genes sgsh
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sgsh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016250	N-sulfoglucosamine sulfohydrolase activity	SGSH	IDA		Human	PMID:15146460
Molecular Function	GO:0016250	N-sulfoglucosamine sulfohydrolase activity	SGSH	IDA		Human	PMID:7493035
Molecular Function	GO:0016250	N-sulfoglucosamine sulfohydrolase activity	Sgsh	IMP	MGI:MGI:2151181	Mouse	PMID:11181566
Molecular Function	GO:0016250	N-sulfoglucosamine sulfohydrolase activity	sgsh	IMP	ZFIN:ZDB-GENO-220906-1	Zfish	PMID:34073041
Molecular Function	GO:0005515	protein binding	SGSH	IPI	UniProtKB:Q8NBK3	Human	PMID:15962010
Molecular Function	GO:0005515	protein binding	Sgsh	IPI	PR:Q8BPG6	Mouse	PMID:15962010
Molecular Function	GO:0005515	protein binding	Sgsh	IPI	PR:Q8R0F3	Mouse	PMID:15962010
Molecular Function	GO:0008484	sulfuric ester hydrolase activity	Sgsh	IDA		Mouse	PMID:15962010
Cellular Component	GO:0070062	extracellular exosome	SGSH	HDA		Human	PMID:23533145
Cellular Component	GO:0043202	lysosomal lumen	Sgsh	IMP	MGI:MGI:2151181	Mouse	PMID:10561464
Cellular Component	GO:0005764	lysosome	SGSH	IDA		Human	PMID:15146460
Biological Process	GO:0008340	determination of adult lifespan	Sgsh	IGI	MGI:MGI:1351641	Mouse	PMID:22867887
Biological Process	GO:0006027	glycosaminoglycan catabolic process	SGSH	IDA		Human	PMID:15146460
Biological Process	GO:0006027	glycosaminoglycan catabolic process	SGSH	IDA		Human	PMID:7493035
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	SGSH	IMP		Human	PMID:15146460
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	Sgsh	IMP	MGI:MGI:1856041	Mouse	PMID:11273777
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	Sgsh	IMP	MGI:MGI:2151181	Mouse	PMID:10561464
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	sgsh	IMP	ZFIN:ZDB-GENO-220906-1	Zfish	PMID:34073041
Biological Process	GO:0007626	locomotory behavior	sgsh	IMP	ZFIN:ZDB-GENO-220906-1	Zfish	PMID:34073041
Biological Process	GO:0001774	microglial cell activation	sgsh	IMP	ZFIN:ZDB-GENO-220906-1	Zfish	PMID:34073041
Biological Process	GO:0061744	motor behavior	Sgsh	IGI	MGI:MGI:1351641	Mouse	PMID:22867887
Biological Process	GO:0001966	thigmotaxis	sgsh	IMP	ZFIN:ZDB-GENO-220906-1	Zfish	PMID:34073041

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern