Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SETD1B
  • Mouse genes Setd1b
  • Rat genes Setd1b
  • Zfish genes setd1ba
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setd1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	SETD1B	IDA		Human	PMID:17355966
Molecular Function	GO:0005515	protein binding	SETD1B	IPI	UniProtKB:P24928	Human	PMID:17998332
Molecular Function	GO:0005515	protein binding	SETD1B	IPI	UniProtKB:Q6UXN9	Human	PMID:17998332
Molecular Function	GO:0005515	protein binding	SETD1B	IPI	UniProtKB:Q9UBL3	Human	PMID:17998332
Molecular Function	GO:0005515	protein binding	SETD1B	IPI	UniProtKB:P61964	Human	PMID:22266653
Molecular Function	GO:0005515	protein binding	SETD1B	IPI	UniProtKB:P61964	Human	PMID:22665483
Cellular Component	GO:0035097	histone methyltransferase complex	SETD1B	IDA		Human	PMID:17355966
Cellular Component	GO:0005654	nucleoplasm	SETD1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Setd1b	IDA		Mouse	PMID:24550110
Cellular Component	GO:0048188	Set1C/COMPASS complex	SETD1B	IPI		Human	PMID:23508102
Cellular Component	GO:0048188	Set1C/COMPASS complex	SETD1B	IDA		Human	PMID:17998332
Cellular Component	GO:0048188	Set1C/COMPASS complex	SETD1B	IDA		Human	PMID:18838538
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	setd1ba	IMP		Zfish	PMID:24240475

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern