About   Help   FAQ
Setd1b
Gene Detail
 Symbol
Name
ID
Setd1b
SET domain containing 1B
MGI:2652820
Synonyms KMT2G, MGC:39035, mKIAA1076
Feature Type protein coding gene
Genetic Map
Chromosome 5
62.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:123142193-123167435 bp, + strand
From VEGA annotation of GRCm38

  25243 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Setd1b
Alleles
and
phenotypes
All alleles(17) : Targeted(1) Gene trapped(16)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process chromatin modification, methylation, ...
Component chromosome, nucleus
Function histone-lysine N-methyltransferase activity, methyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (125)    Tissues (125)    Images (1)
Theiler Stages: 1, 2, 3, 4, 5, 21, 22, 28
Assay TypeResults
RNA in situ 114
RT-PCR 11
cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000017166 (Evidence)
Ensembl Gene ModelENSMUSG00000038384 (Evidence)
Entrez Gene208043 (Evidence)
NIA Mouse Gene IndexU042689, U208900
EC2.1.1.43
Consensus CDS ProjectCCDS59684.1
International Mouse Knockout Project StatusSetd1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017166 VEGA Gene Model | MGI Sequence Detail 25243 C57BL/6J ±  kb
transcript OTTMUST00000096989 VEGA | MGI Sequence Detail 7663 Not Applicable 
polypeptide OTTMUSP00000054284 VEGA | MGI Sequence Detail 1985 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(7) UniProt(3)
Polymorphisms SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024657 COMPASS complex Set1 subunit, N-SET domain
InterPro IPR015722 Histone-lysine N-methyltransferase
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR003616 Post-SET domain
InterPro IPR000504 RNA recognition motif domain
InterPro IPR001214 SET domain
Protein Ontology PR:000014720 histone-lysine N-methyltransferase SETD1B
References (Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGI:2140755

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory