Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEPTIN12
  • Mouse genes Septin12
  • Rat genes Septin12
  • Zfish genes septin12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Septin12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005525	GTP binding	SEPTIN12	IDA		Human	PMID:18443421
Molecular Function	GO:0042802	identical protein binding	SEPTIN12	IPI	UniProtKB:Q8IYM1	Human	PMID:25588830
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q14141	Human	PMID:18047794
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q9NVA2	Human	PMID:18443421
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q8WYJ6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:O43236	Human	PMID:25588830
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q14141	Human	PMID:25588830
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q15019	Human	PMID:25588830
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q16181	Human	PMID:25588830
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:O43236	Human	PMID:25775403
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q14141	Human	PMID:25775403
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q9NPE6	Human	PMID:25775403
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q16181	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q8WYJ6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q99719	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q8WYJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q99719	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q9UHP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN12	IPI	UniProtKB:Q99719	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Septin12	IPI	UniProtKB:O43236	Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0005515	protein binding	Septin12	IPI	UniProtKB:Q15019	Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0005515	protein binding	Septin12	IPI	UniProtKB:Q16181	Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0005515	protein binding	Septin12	IPI	UniProtKB:Q8WYJ6	Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0005515	protein binding	Septin12	IPI	UniProtKB:Q92599	Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0005515	protein binding	Septin12	IPI	UniProtKB:Q9JJM9	Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0042803	protein homodimerization activity	SEPTIN12	IPI	UniProtKB:Q8IYM1	Human	PMID:18443421
Cellular Component	GO:0015630	microtubule cytoskeleton	SEPTIN12	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030496	midbody	SEPTIN12	IDA		Human	PMID:18047794
Cellular Component	GO:0048471	perinuclear region of cytoplasm	SEPTIN12	IDA		Human	PMID:18047794
Cellular Component	GO:0031105	septin complex	SEPTIN12	IDA		Human	PMID:25588830
Cellular Component	GO:0097227	sperm annulus	SEPTIN12	IDA		Human	PMID:22275165
Cellular Component	GO:0005819	spindle	SEPTIN12	IDA		Human	PMID:18047794
Biological Process	GO:0030317	flagellated sperm motility	Septin12	IMP		Mouse	MGI:MGI:5648570|PMID:25588830

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern