Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SENP2
  • Mouse genes Senp2
  • Rat genes Senp2
  • Zfish genes senp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Senp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016929	deSUMOylase activity	Senp2	IDA		Mouse	MGI:MGI:2670563|PMID:12419228
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:P49790	Human	PMID:11896061
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:P63165	Human	PMID:15296745
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:P55854	Human	PMID:17099700
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:P61956	Human	PMID:17099700
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:P63165	Human	PMID:17099700
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q9Y6K9	Human	PMID:20098747
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q13330	Human	PMID:21965678
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:P55854	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:P61956	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q15041	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q6RW13	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q8IVP5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q8N205	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q8N6L0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q8WW34	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:P53701	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:P55056	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q5T9G4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q6RW13-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q8N3Y7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q8N6L0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q8WW34-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q96CM8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP2	IPI	UniProtKB:Q9UBN6	Human	PMID:32296183
Molecular Function	GO:0019904	protein domain specific binding	Senp2	IPI	RGD:620859	Rat	PMID:10944533|RGD:1299408
Molecular Function	GO:0070139	SUMO-specific endopeptidase activity	SENP2	IDA		Human	PMID:11896061
Molecular Function	GO:0070139	SUMO-specific endopeptidase activity	SENP2	EXP		Human	PMID:16608850
Molecular Function	GO:0070139	SUMO-specific endopeptidase activity	SENP2	EXP		Human	PMID:17591783
Cellular Component	GO:0005829	cytosol	SENP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	Senp2	IDA		Mouse	PMID:20417598
Cellular Component	GO:0005643	nuclear pore	SENP2	IDA		Human	PMID:12192048
Cellular Component	GO:0016605	PML body	Senp2	IDA		Mouse	MGI:MGI:2670563|PMID:12419228
Biological Process	GO:0009950	dorsal/ventral axis specification	Senp2	IDA		Rat	PMID:10944533|RGD:1299408
Biological Process	GO:0045444	fat cell differentiation	Senp2	IDA		Mouse	MGI:MGI:4461072|PMID:20194620
Biological Process	GO:0007507	heart development	Senp2	IMP	MGI:MGI:3818535	Mouse	PMID:20417598
Biological Process	GO:0060711	labyrinthine layer development	Senp2	IMP	MGI:MGI:3832730	Mouse	PMID:19090619
Biological Process	GO:0035562	negative regulation of chromatin binding	Senp2	IMP	MGI:MGI:3818535	Mouse	PMID:20417598
Biological Process	GO:0032091	negative regulation of protein binding	Senp2	IDA		Rat	PMID:10944533|RGD:1299408
Biological Process	GO:0031397	negative regulation of protein ubiquitination	SENP2	IDA		Human	PMID:22028379
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Senp2	IDA		Rat	PMID:10944533|RGD:1299408
Biological Process	GO:0031398	positive regulation of protein ubiquitination	SENP2	IMP		Human	PMID:22028379
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Senp2	IMP		Mouse	PMID:20417598
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Senp2	IGI	MGI:MGI:1195985	Mouse	PMID:20417598
Biological Process	GO:0031648	protein destabilization	SENP2	IMP		Human	PMID:22028379
Biological Process	GO:0016926	protein desumoylation	SENP2	IDA		Human	PMID:20194620
Biological Process	GO:0016926	protein desumoylation	SENP2	IMP		Human	PMID:21965678
Biological Process	GO:0016926	protein desumoylation	SENP2	IMP		Human	PMID:22028379
Biological Process	GO:0016926	protein desumoylation	Senp2	IDA		Mouse	MGI:MGI:4461072|PMID:20194620
Biological Process	GO:0016926	protein desumoylation	Senp2	IDA		Mouse	MGI:MGI:2670563|PMID:12419228
Biological Process	GO:0016926	protein desumoylation	Senp2	IMP	MGI:MGI:3818535	Mouse	PMID:20417598
Biological Process	GO:0016926	protein desumoylation	Senp2	IDA		Mouse	PMID:15767674
Biological Process	GO:0032875	regulation of DNA endoreduplication	Senp2	IMP	MGI:MGI:3832730	Mouse	PMID:19090619
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	Senp2	IMP	MGI:MGI:3832730	Mouse	PMID:19090619
Biological Process	GO:0051246	regulation of protein metabolic process	Senp2	IDA		Rat	PMID:10944533|RGD:1299408
Biological Process	GO:0060712	spongiotrophoblast layer development	Senp2	IMP	MGI:MGI:3832730	Mouse	PMID:19090619
Biological Process	GO:0060707	trophoblast giant cell differentiation	Senp2	IMP	MGI:MGI:3832730	Mouse	PMID:19090619

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern