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Gene Ontology Browser
Term Detail
GO term:protein destabilization
Synonym: negative regulation of protein stability
Synonym: protein destabilisation
GO id:GO:0031648
Definition:Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of protein stability
                                        is-amaintenance of unfolded protein +
                                        is-aprotein destabilization [GO:0031648] (41 genes, 47 annotations)
                                        is-aprotein stabilization

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.08
The Jackson Laboratory