Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SENP1
  • Mouse genes Senp1
  • Rat genes Senp1
  • Zfish genes senp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Senp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016929	deSUMOylase activity	Senp1	IMP		Mouse	MGI:MGI:4452185|PMID:20233849
Molecular Function	GO:0016929	deSUMOylase activity	Senp1	IDA		Mouse	PMID:22942423
Molecular Function	GO:0005515	protein binding	SENP1	IPI	UniProtKB:P61956	Human	PMID:17099698
Molecular Function	GO:0005515	protein binding	SENP1	IPI	UniProtKB:P63165	Human	PMID:17099698
Molecular Function	GO:0005515	protein binding	SENP1	IPI	UniProtKB:Q13330	Human	PMID:21965678
Molecular Function	GO:0005515	protein binding	SENP1	IPI	UniProtKB:P63165	Human	PMID:22878415
Molecular Function	GO:0005515	protein binding	SENP1	IPI	UniProtKB:P61956	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SENP1	IPI	UniProtKB:P63165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Senp1	IPI	PR:P23611	Mouse	PMID:22942423
Molecular Function	GO:0070139	SUMO-specific endopeptidase activity	SENP1	EXP		Human	PMID:16608850
Molecular Function	GO:0070139	SUMO-specific endopeptidase activity	SENP1	EXP		Human	PMID:17591783
Cellular Component	GO:0005925	focal adhesion	SENP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	SENP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SENP1	IDA		Human	GO_REF:0000052
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	SENP1	IMP		Human	PMID:1087798
Biological Process	GO:0097190	apoptotic signaling pathway	SENP1	IMP		Human	PMID:1087798
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Senp1	IMP	MGI:MGI:3818522	Mouse	PMID:17981124
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SENP1	IGI	UniProtKB:Q16665	Human	PMID:17981124
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Senp1	IMP	MGI:MGI:3818522	Mouse	PMID:17981124
Biological Process	GO:0016926	protein desumoylation	SENP1	IMP		Human	PMID:21965678
Biological Process	GO:0016926	protein desumoylation	Senp1	IDA		Mouse	MGI:MGI:4452185|PMID:20233849
Biological Process	GO:0016926	protein desumoylation	Senp1	IDA		Mouse	PMID:17981124
Biological Process	GO:0016926	protein desumoylation	Senp1	IMP	MGI:MGI:3582213	Mouse	PMID:15923632
Biological Process	GO:0016926	protein desumoylation	Senp1	IDA		Mouse	PMID:15767674
Biological Process	GO:0016926	protein desumoylation	Senp1	IDA		Mouse	PMID:22942423
Biological Process	GO:0010724	regulation of definitive erythrocyte differentiation	Senp1	IMP	MGI:MGI:3818522	Mouse	PMID:17981124

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern