Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEC61B
  • Mouse genes Sec61b
  • Rat genes Sec61b
  • Zfish genes sec61b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sec61b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048408	epidermal growth factor binding	SEC61B	IPI	UniProtKB:P00533	Human	PMID:19602593
Molecular Function	GO:0005515	protein binding	SEC61B	IPI	UniProtKB:P51572	Human	PMID:18555783
Molecular Function	GO:0005515	protein binding	SEC61B	IPI	UniProtKB:Q15629	Human	PMID:19121997
Molecular Function	GO:0005515	protein binding	SEC61B	IPI	UniProtKB:Q12154	Human	PMID:19675567
Molecular Function	GO:0005515	protein binding	SEC61B	IPI	UniProtKB:Q12154	Human	PMID:21866104
Molecular Function	GO:0005515	protein binding	SEC61B	IPI	UniProtKB:P60059,UniProtKB:P61619,UniProtKB:P69849,UniProtKB:Q15155,UniProtKB:Q5JPE7,UniProtKB:Q969V3,UniProtKB:Q96A33,UniProtKB:Q9BVK8,UniProtKB:Q9UM00	Human	PMID:32820719
Molecular Function	GO:0005515	protein binding	SEC61B	IPI	UniProtKB:P13569	Human	PMID:9792704
Molecular Function	GO:0005515	protein binding	Sec61b	IPI	UniProtKB:P07307	Mouse	MGI:MGI:6120598|PMID:11408579
Molecular Function	GO:0043022	ribosome binding	SEC61B	IDA		Human	PMID:32820719
Molecular Function	GO:0043022	ribosome binding	Sec61b	IDA		Mouse	PMID:16705175
Molecular Function	GO:0003723	RNA binding	SEC61B	HDA		Human	PMID:22658674
Cellular Component	GO:0005783	endoplasmic reticulum	SEC61B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	SEC61B	IDA		Human	PMID:18555783
Cellular Component	GO:0005783	endoplasmic reticulum	Sec61b	IDA		Mouse	PMID:23439682
Cellular Component	GO:0005783	endoplasmic reticulum	Sec61b	IDA		Mouse	PMID:23093945
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SEC61B	IDA		Human	PMID:27044890
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	SEC61B	IDA		Human	PMID:17707796
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	Sec61b	IDA		Mouse	MGI:MGI:6467680|PMID:17707796
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	Sec61b	IDA		Mouse	MGI:MGI:6120598|PMID:11408579
Cellular Component	GO:0016020	membrane	SEC61B	IDA		Human	PMID:22375059
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	SEC61B	IMP		Human	PMID:17215517
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	SEC61B	IDA		Human	PMID:8945469

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern