Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCYL1
  • Mouse genes Scyl1
  • Rat genes Scyl1
  • Zfish genes scyl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scyl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	SCYL1	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	SCYL1	IPI	UniProtKB:P63010	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Scyl1	IPI	UniProtKB:Q8BRM2	Mouse	MGI:MGI:3690143|PMID:12783284
Molecular Function	GO:0005515	protein binding	Scyl1	IPI	UniProtKB:O35142|UniProtKB:P23514|UniProtKB:P53618	Mouse	MGI:MGI:3847866|PMID:18556652
Cellular Component	GO:0005801	cis-Golgi network	SCYL1	IDA		Human	PMID:18556652
Cellular Component	GO:0030126	COPI vesicle coat	SCYL1	IDA		Human	PMID:18556652
Cellular Component	GO:0030126	COPI vesicle coat	Scyl1	IDA		Mouse	MGI:MGI:3847866|PMID:18556652
Cellular Component	GO:0005737	cytoplasm	Scyl1	IDA		Mouse	MGI:MGI:3690143|PMID:12783284
Cellular Component	GO:0005829	cytosol	SCYL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	SCYL1	IDA		Human	PMID:18556652
Cellular Component	GO:0005794	Golgi apparatus	SCYL1	IDA		Human	PMID:18556652
Cellular Component	GO:0016020	membrane	SCYL1	HDA		Human	PMID:19946888
Biological Process	GO:0006954	inflammatory response	Scyl1	IGI	MGI:MGI:1921385	Mouse	PMID:29437892
Biological Process	GO:0006954	inflammatory response	Scyl1	IMP	MGI:MGI:5469960	Mouse	PMID:29437892
Biological Process	GO:0048666	neuron development	Scyl1	IGI	MGI:MGI:1921385	Mouse	PMID:29437892
Biological Process	GO:0008104	protein localization	Scyl1	IGI	MGI:MGI:1921385	Mouse	PMID:29437892
Biological Process	GO:0008104	protein localization	Scyl1	IMP	MGI:MGI:5469960	Mouse	PMID:29437892
Biological Process	GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	SCYL1	IDA		Human	PMID:18556652
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Scyl1	IMP	MGI:MGI:5469960	Mouse	PMID:29437892
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Scyl1	IGI	MGI:MGI:1921385	Mouse	PMID:29437892

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern