Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCUBE1
  • Mouse genes Scube1
  • Rat genes Scube1
  • Zfish genes scube1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scube1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SCUBE1	IDA		Human	PMID:12270931
Molecular Function	GO:0042802	identical protein binding	SCUBE1	IPI	UniProtKB:Q8IWY4	Human	PMID:12270931
Molecular Function	GO:0005515	protein binding	SCUBE1	IPI	UniProtKB:Q9NQ36	Human	PMID:12270931
Cellular Component	GO:0009986	cell surface	SCUBE1	IDA		Human	PMID:12270931
Cellular Component	GO:0009897	external side of plasma membrane	SCUBE1	IDA		Human	PMID:12270931
Cellular Component	GO:0005615	extracellular space	SCUBE1	IDA		Human	PMID:12270931
Cellular Component	GO:0005886	plasma membrane	SCUBE1	IDA		Human	PMID:12270931
Cellular Component	GO:0005886	plasma membrane	scube1	IDA		Zfish	PMID:26699903
Biological Process	GO:0030509	BMP signaling pathway	scube1	IDA		Zfish	PMID:26699903
Biological Process	GO:0055001	muscle cell development	scube1	IGI	ZFIN:ZDB-MRPHLNO-050510-1,ZFIN:ZDB-MRPHLNO-120813-6,ZFIN:ZDB-MRPHLNO-120813-7	Zfish	PMID:22609552
Biological Process	GO:0055001	muscle cell development	scube1	IGI	ZFIN:ZDB-GENO-070808-35,ZFIN:ZDB-MRPHLNO-120813-6	Zfish	PMID:22609552
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Scube1	IDA		Mouse	PMID:25639508
Biological Process	GO:0060215	primitive hemopoiesis	scube1	IMP	ZFIN:ZDB-MRPHLNO-130404-1	Zfish	PMID:23271740
Biological Process	GO:0007224	smoothened signaling pathway	scube1	IGI	ZFIN:ZDB-GENE-980526-166,ZFIN:ZDB-MRPHLNO-050510-1,ZFIN:ZDB-MRPHLNO-120813-6,ZFIN:ZDB-MRPHLNO-120813-7	Zfish	PMID:22609552
Biological Process	GO:0007224	smoothened signaling pathway	scube1	IGI	ZFIN:ZDB-MRPHLNO-050510-1,ZFIN:ZDB-MRPHLNO-120813-6,ZFIN:ZDB-MRPHLNO-120813-7	Zfish	PMID:22609552

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern