Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCN7A
  • Mouse genes Scn7a
  • Rat genes Scn7a
  • Zfish genes scn1laa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scn7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Scn7a	IPI	UniProtKB:Q62696	Mouse	MGI:MGI:5448583|PMID:23022437
Molecular Function	GO:0005272	sodium channel activity	Scn7a	IDA		Mouse	PMID:16223844
Molecular Function	GO:0005248	voltage-gated sodium channel activity	scn1laa	IMP	ZFIN:ZDB-MRPHLNO-050816-1	Zfish	PMID:15673553
Cellular Component	GO:0097386	glial cell projection	Scn7a	IDA		Mouse	PMID:16223844
Cellular Component	GO:0005886	plasma membrane	Scn7a	IDA		Mouse	PMID:16223844
Biological Process	GO:0019725	cellular homeostasis	Scn7a	IDA		Mouse	PMID:16223844
Biological Process	GO:0019725	cellular homeostasis	Scn7a	IMP		Mouse	PMID:16223844
Biological Process	GO:0009617	response to bacterium	Scn7a	IEP		Mouse	PMID:23012479
Biological Process	GO:0055078	sodium ion homeostasis	Scn7a	IDA		Mouse	PMID:16223844
Biological Process	GO:0055078	sodium ion homeostasis	Scn7a	IMP		Mouse	PMID:16223844

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern