Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCN5A
  • Mouse genes Scn5a
  • Rat genes Scn5a
  • Zfish genes scn12aa,scn5lab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scn5a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030506	ankyrin binding	SCN5A	IDA		Human	PMID:15579534
Molecular Function	GO:0030506	ankyrin binding	Scn5a	IDA		Rat	PMID:15579534|RGD:6484228
Molecular Function	GO:0030506	ankyrin binding	Scn5a	IPI	UniProtKB:O70511	Rat	PMID:15579534|RGD:6484228
Molecular Function	GO:0005516	calmodulin binding	SCN5A	IPI	UniProtKB:P0DP23	Human	PMID:21167176
Molecular Function	GO:0005516	calmodulin binding	SCN5A	IPI	UniProtKB:P0DP24	Human	PMID:21167176
Molecular Function	GO:0005516	calmodulin binding	SCN5A	IPI	UniProtKB:P0DP25	Human	PMID:21167176
Molecular Function	GO:0019899	enzyme binding	SCN5A	IPI	UniProtKB:Q8N335	Human	PMID:19666841
Molecular Function	GO:0017134	fibroblast growth factor binding	SCN5A	IPI	UniProtKB:P61150	Human	PMID:12401812
Molecular Function	GO:0017134	fibroblast growth factor binding	Scn5a	IPI	RGD:620163	Rat	PMID:12401812|RGD:6484231
Molecular Function	GO:0050998	nitric-oxide synthase binding	SCN5A	IPI	UniProtKB:P29476	Human	PMID:18591664
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:P68510	Human	PMID:16728661
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:Q04917	Human	PMID:16728661
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:P26045	Human	PMID:16930557
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:Q9HD47	Human	PMID:18184654
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:Q13424	Human	PMID:18591664
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:O43707	Human	PMID:19943616
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:P12814	Human	PMID:19943616
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:Q08043	Human	PMID:19943616
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:Q13557	Human	PMID:22514276
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:P61328-2	Human	PMID:22705208
Molecular Function	GO:0005515	protein binding	SCN5A	IPI	UniProtKB:Q92913	Human	PMID:26392562
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	UniProtKB:P70377	Mouse	MGI:MGI:5437408|PMID:21817159
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	UniProtKB:Q9JI91	Mouse	MGI:MGI:5640949|PMID:19943616
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	UniProtKB:Q9JIB0	Mouse	MGI:MGI:5426778|PMID:18184654
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	UniProtKB:Q8BHK2	Mouse	MGI:MGI:5426776|PMID:20042427
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	UniProtKB:Q4U4S6	Mouse	MGI:MGI:6114554|PMID:29306897
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	PR:Q8C8R3	Mouse	PMID:15272007
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	PR:P15116	Mouse	PMID:15272007
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	RGD:3631	Rat	PMID:11238277|RGD:6484234
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	RGD:3633	Rat	PMID:11238277|RGD:6484234
Molecular Function	GO:0005515	protein binding	Scn5a	IPI	UniProtKB:Q562C0	Rat	PMID:19661460|RGD:6784504
Molecular Function	GO:0019904	protein domain specific binding	SCN5A	IPI	UniProtKB:P35609	Human	PMID:19943616
Molecular Function	GO:0019901	protein kinase binding	SCN5A	IPI	UniProtKB:Q13557	Human	PMID:22514276
Molecular Function	GO:0097110	scaffold protein binding	SCN5A	IPI	UniProtKB:P56539	Human	PMID:17060380
Molecular Function	GO:0097110	scaffold protein binding	Scn5a	IPI	UniProtKB:Q61234	Mouse	MGI:MGI:5499724|PMID:18591664
Molecular Function	GO:0044325	transmembrane transporter binding	SCN5A	IPI	UniProtKB:Q8IWT1	Human	PMID:17592081
Molecular Function	GO:0044325	transmembrane transporter binding	SCN5A	IPI	UniProtKB:Q9NY72	Human	PMID:20042427
Molecular Function	GO:0044325	transmembrane transporter binding	SCN5A	IPI	UniProtKB:Q9Y5Y9	Human	PMID:24998131
Molecular Function	GO:0031625	ubiquitin protein ligase binding	SCN5A	IPI	UniProtKB:Q96PU5	Human	PMID:15217910
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Scn5a	IPI	PR:Q8CFI0	Mouse	PMID:32175648
Molecular Function	GO:0005248	voltage-gated sodium channel activity	SCN5A	IDA		Human	PMID:14500339
Molecular Function	GO:0005248	voltage-gated sodium channel activity	SCN5A	IDA		Human	PMID:19074138
Molecular Function	GO:0005248	voltage-gated sodium channel activity	SCN5A	IDA		Human	PMID:19808477
Molecular Function	GO:0005248	voltage-gated sodium channel activity	SCN5A	IDA		Human	PMID:19943616
Molecular Function	GO:0005248	voltage-gated sodium channel activity	SCN5A	IDA		Human	PMID:21895525
Molecular Function	GO:0005248	voltage-gated sodium channel activity	SCN5A	IDA		Human	PMID:22514276
Molecular Function	GO:0005248	voltage-gated sodium channel activity	SCN5A	IMP		Human	PMID:23085483
Molecular Function	GO:0005248	voltage-gated sodium channel activity	SCN5A	IMP		Human	PMID:26279430
Molecular Function	GO:0005248	voltage-gated sodium channel activity	SCN5A	IMP		Human	PMID:26392562
Molecular Function	GO:0005248	voltage-gated sodium channel activity	Scn5a	IDA		Mouse	PMID:32175648
Molecular Function	GO:0005248	voltage-gated sodium channel activity	scn5lab	IDA		Zfish	PMID:17623065
Molecular Function	GO:0086060	voltage-gated sodium channel activity involved in AV node cell action potential	SCN5A	IMP		Human	PMID:18616619
Molecular Function	GO:0086061	voltage-gated sodium channel activity involved in bundle of His cell action potential	SCN5A	IMP		Human	PMID:18065446
Molecular Function	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	SCN5A	IDA		Human	PMID:18065446
Molecular Function	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	SCN5A	IMP		Human	PMID:18616619
Molecular Function	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	SCN5A	IMP		Human	PMID:21895525
Molecular Function	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	SCN5A	IMP		Human	PMID:22529811
Molecular Function	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	Scn5a	IMP	MGI:MGI:2179753	Mouse	PMID:11972032
Molecular Function	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	Scn5a	IMP		Rat	PMID:29457789|RGD:126781740
Molecular Function	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential	SCN5A	IMP		Human	PMID:22766342
Molecular Function	GO:0086063	voltage-gated sodium channel activity involved in SA node cell action potential	SCN5A	IMP		Human	PMID:18616619
Molecular Function	GO:0086063	voltage-gated sodium channel activity involved in SA node cell action potential	Scn5a	IMP	MGI:MGI:2179753	Mouse	PMID:15932895
Cellular Component	GO:0005901	caveola	SCN5A	IDA		Human	PMID:23420830
Cellular Component	GO:0009986	cell surface	SCN5A	IDA		Human	PMID:14500339
Cellular Component	GO:0009986	cell surface	SCN5A	IDA		Human	PMID:19666841
Cellular Component	GO:0009986	cell surface	SCN5A	IDA		Human	PMID:19943616
Cellular Component	GO:0009986	cell surface	Scn5a	IDA		Mouse	MGI:MGI:3763979|PMID:17884088
Cellular Component	GO:0005783	endoplasmic reticulum	SCN5A	IDA		Human	PMID:22529811
Cellular Component	GO:0014704	intercalated disc	SCN5A	IDA		Human	PMID:15579534
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Mouse	MGI:MGI:3763979|PMID:17884088
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Mouse	MGI:MGI:5437408|PMID:21817159
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Mouse	MGI:MGI:5426778|PMID:18184654
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Mouse	PMID:20877009
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Mouse	PMID:15272007
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Mouse	PMID:18178574
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Mouse	PMID:26187182
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Mouse	PMID:15746173
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Rat	PMID:15579534|RGD:6484228
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Rat	PMID:18180363|RGD:6767295
Cellular Component	GO:0014704	intercalated disc	Scn5a	IDA		Rat	PMID:19661460|RGD:6784504
Cellular Component	GO:0016328	lateral plasma membrane	Scn5a	IDA		Mouse	MGI:MGI:5437408|PMID:21817159
Cellular Component	GO:0016020	membrane	SCN5A	IDA		Human	PMID:19074138
Cellular Component	GO:0005730	nucleolus	SCN5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SCN5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SCN5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SCN5A	IDA		Human	PMID:16728661
Cellular Component	GO:0005886	plasma membrane	SCN5A	IDA		Human	PMID:17060380
Cellular Component	GO:0005886	plasma membrane	SCN5A	IDA		Human	PMID:22529811
Cellular Component	GO:0005886	plasma membrane	SCN5A	IMP		Human	PMID:23085483
Cellular Component	GO:0005886	plasma membrane	SCN5A	IMP		Human	PMID:26279430
Cellular Component	GO:0005886	plasma membrane	Scn5a	IDA		Mouse	PMID:15746173
Cellular Component	GO:0005886	plasma membrane	Scn5a	IDA		Mouse	PMID:32175648
Cellular Component	GO:0042383	sarcolemma	SCN5A	IDA		Human	PMID:17060380
Cellular Component	GO:0034706	sodium channel complex	Scn5a	IPI	UniProtKB:A2APX8	Mouse	PMID:15272007
Cellular Component	GO:0034706	sodium channel complex	Scn5a	IPI	PR:P97952	Mouse	PMID:15272007
Cellular Component	GO:0034706	sodium channel complex	Scn5a	IPI	UniProtKB:Q9WTU3	Mouse	PMID:15272007
Cellular Component	GO:0030315	T-tubule	SCN5A	IDA		Human	PMID:15579534
Cellular Component	GO:0030315	T-tubule	Scn5a	IDA		Mouse	PMID:18178574
Cellular Component	GO:0030315	T-tubule	Scn5a	IDA		Mouse	PMID:15746173
Cellular Component	GO:0030315	T-tubule	Scn5a	IDA		Rat	PMID:15579534|RGD:6484228
Cellular Component	GO:0001518	voltage-gated sodium channel complex	SCN5A	IDA		Human	PMID:19808477
Cellular Component	GO:0001518	voltage-gated sodium channel complex	SCN5A	IDA		Human	PMID:20042427
Cellular Component	GO:0001518	voltage-gated sodium channel complex	SCN5A	IDA		Human	PMID:21051419
Cellular Component	GO:0030018	Z disc	SCN5A	IDA		Human	PMID:19943616
Biological Process	GO:0086014	atrial cardiac muscle cell action potential	SCN5A	IMP		Human	PMID:18065446
Biological Process	GO:0086016	AV node cell action potential	SCN5A	IMP		Human	PMID:18616619
Biological Process	GO:0086067	AV node cell to bundle of His cell communication	SCN5A	IMP		Human	PMID:10471492
Biological Process	GO:0003360	brainstem development	Scn5a	IEP		Rat	PMID:22331407|RGD:6484221
Biological Process	GO:0086043	bundle of His cell action potential	SCN5A	IMP		Human	PMID:18065446
Biological Process	GO:0086002	cardiac muscle cell action potential involved in contraction	SCN5A	IMP		Human	PMID:21895525
Biological Process	GO:0060048	cardiac muscle contraction	SCN5A	IMP		Human	PMID:18065446
Biological Process	GO:0060048	cardiac muscle contraction	SCN5A	IMP		Human	PMID:21895525
Biological Process	GO:0060048	cardiac muscle contraction	SCN5A	IMP		Human	PMID:22529811
Biological Process	GO:0003231	cardiac ventricle development	Scn5a	IMP	MGI:MGI:2179753	Mouse	PMID:11972032
Biological Process	GO:0071277	cellular response to calcium ion	SCN5A	IDA		Human	PMID:19074138
Biological Process	GO:0021549	cerebellum development	Scn5a	IEP		Rat	PMID:22331407|RGD:6484221
Biological Process	GO:0001947	heart looping	scn12aa	IMP	ZFIN:ZDB-MRPHLNO-100616-2	Zfish	PMID:20339120
Biological Process	GO:0001947	heart looping	scn12aa	IMP	ZFIN:ZDB-MRPHLNO-100616-1	Zfish	PMID:20339120
Biological Process	GO:0001947	heart looping	scn12aa	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:20339120
Biological Process	GO:0001947	heart looping	scn12aa	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-120105-1	Zfish	PMID:20339120
Biological Process	GO:0001947	heart looping	scn5lab	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:20339120
Biological Process	GO:0001947	heart looping	scn5lab	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-120105-1	Zfish	PMID:20339120
Biological Process	GO:0001947	heart looping	scn5lab	IMP	ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:20339120
Biological Process	GO:0001947	heart looping	scn5lab	IMP	ZFIN:ZDB-MRPHLNO-120105-1	Zfish	PMID:20339120
Biological Process	GO:0003007	heart morphogenesis	scn12aa	IMP	ZFIN:ZDB-MRPHLNO-100616-1	Zfish	PMID:20339120
Biological Process	GO:0003007	heart morphogenesis	scn12aa	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-120105-1	Zfish	PMID:20339120
Biological Process	GO:0003007	heart morphogenesis	scn12aa	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:20339120
Biological Process	GO:0003007	heart morphogenesis	scn12aa	IMP	ZFIN:ZDB-MRPHLNO-100616-2	Zfish	PMID:20339120
Biological Process	GO:0003007	heart morphogenesis	scn5lab	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:20339120
Biological Process	GO:0003007	heart morphogenesis	scn5lab	IMP	ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:20339120
Biological Process	GO:0003007	heart morphogenesis	scn5lab	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-120105-1	Zfish	PMID:20339120
Biological Process	GO:0003007	heart morphogenesis	scn5lab	IMP	ZFIN:ZDB-MRPHLNO-120105-1	Zfish	PMID:20339120
Biological Process	GO:0051899	membrane depolarization	SCN5A	IDA		Human	PMID:14500339
Biological Process	GO:0051899	membrane depolarization	SCN5A	IDA		Human	PMID:21051419
Biological Process	GO:0051899	membrane depolarization	SCN5A	IDA		Human	PMID:21895525
Biological Process	GO:0086010	membrane depolarization during action potential	SCN5A	IDA		Human	PMID:14500339
Biological Process	GO:0086010	membrane depolarization during action potential	SCN5A	IDA		Human	PMID:18065446
Biological Process	GO:0086010	membrane depolarization during action potential	SCN5A	IDA		Human	PMID:22529811
Biological Process	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential	SCN5A	IMP		Human	PMID:18065446
Biological Process	GO:0086045	membrane depolarization during AV node cell action potential	SCN5A	IMP		Human	PMID:18616619
Biological Process	GO:0086048	membrane depolarization during bundle of His cell action potential	SCN5A	IMP		Human	PMID:18065446
Biological Process	GO:0086012	membrane depolarization during cardiac muscle cell action potential	SCN5A	IMP		Human	PMID:21895525
Biological Process	GO:0086012	membrane depolarization during cardiac muscle cell action potential	Scn5a	IMP		Rat	PMID:29457789|RGD:126781740
Biological Process	GO:0086047	membrane depolarization during Purkinje myocyte cell action potential	SCN5A	IMP		Human	PMID:22766342
Biological Process	GO:0086046	membrane depolarization during SA node cell action potential	SCN5A	IMP		Human	PMID:18616619
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Scn5a	IEP		Rat	PMID:21640979|RGD:6484223
Biological Process	GO:0045760	positive regulation of action potential	Scn5a	IMP		Rat	PMID:22336133|RGD:6484222
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Scn5a	IMP		Rat	PMID:16331678|RGD:6484227
Biological Process	GO:0010460	positive regulation of heart rate	Scn5a	IMP		Rat	PMID:17259145|RGD:6484226
Biological Process	GO:0010765	positive regulation of sodium ion transport	SCN5A	IDA		Human	PMID:14500339
Biological Process	GO:0010765	positive regulation of sodium ion transport	SCN5A	IDA		Human	PMID:18065446
Biological Process	GO:0010765	positive regulation of sodium ion transport	SCN5A	IDA		Human	PMID:19808477
Biological Process	GO:0010765	positive regulation of sodium ion transport	SCN5A	IDA		Human	PMID:22529811
Biological Process	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization	SCN5A	IMP		Human	PMID:19167345
Biological Process	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization	SCN5A	IMP		Human	PMID:22247482
Biological Process	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization	SCN5A	IMP		Human	PMID:19167345
Biological Process	GO:0086004	regulation of cardiac muscle cell contraction	SCN5A	IMP		Human	PMID:22529811
Biological Process	GO:0086004	regulation of cardiac muscle cell contraction	Scn5a	IMP	MGI:MGI:2179753	Mouse	PMID:16172272
Biological Process	GO:0008016	regulation of heart contraction	scn12aa	IMP	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:25282101
Biological Process	GO:0008016	regulation of heart contraction	scn12aa	IMP	ZFIN:ZDB-MRPHLNO-100616-2	Zfish	PMID:20339120
Biological Process	GO:0008016	regulation of heart contraction	scn12aa	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:20339120
Biological Process	GO:0008016	regulation of heart contraction	scn12aa	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-120105-1	Zfish	PMID:20339120
Biological Process	GO:0008016	regulation of heart contraction	scn12aa	IMP	ZFIN:ZDB-MRPHLNO-100616-1	Zfish	PMID:20339120
Biological Process	GO:0008016	regulation of heart contraction	scn5lab	IMP	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:25282101
Biological Process	GO:0008016	regulation of heart contraction	scn5lab	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-120105-1	Zfish	PMID:20339120
Biological Process	GO:0008016	regulation of heart contraction	scn5lab	IMP	ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:20339120
Biological Process	GO:0008016	regulation of heart contraction	scn5lab	IMP	ZFIN:ZDB-MRPHLNO-120105-1	Zfish	PMID:20339120
Biological Process	GO:0008016	regulation of heart contraction	scn5lab	IGI	ZFIN:ZDB-MRPHLNO-100616-1,ZFIN:ZDB-MRPHLNO-100616-3	Zfish	PMID:20339120
Biological Process	GO:0002027	regulation of heart rate	SCN5A	IMP		Human	PMID:10471492
Biological Process	GO:0002027	regulation of heart rate	SCN5A	IMP		Human	PMID:18065446
Biological Process	GO:0002027	regulation of heart rate	SCN5A	IMP		Human	PMID:18616619
Biological Process	GO:0002027	regulation of heart rate	SCN5A	IMP		Human	PMID:21895525
Biological Process	GO:0002027	regulation of heart rate	SCN5A	IMP		Human	PMID:22529811
Biological Process	GO:0002027	regulation of heart rate	SCN5A	IMP		Human	PMID:23085483
Biological Process	GO:0002027	regulation of heart rate	SCN5A	IMP		Human	PMID:26279430
Biological Process	GO:0002027	regulation of heart rate	SCN5A	IMP		Human	PMID:26392562
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	SCN5A	IMP		Human	PMID:21895525
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	Scn5a	IMP	MGI:MGI:2179753	Mouse	PMID:15932895
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	Scn5a	IMP	MGI:MGI:2179753	Mouse	PMID:16172272
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	Scn5a	IMP	MGI:MGI:2179753	Mouse	PMID:11972032
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	Scn5a	IMP	MGI:MGI:2179753	Mouse	PMID:15809371
Biological Process	GO:1902305	regulation of sodium ion transmembrane transport	SCN5A	IDA		Human	PMID:18591664
Biological Process	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	SCN5A	IMP		Human	PMID:18065446
Biological Process	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	SCN5A	IMP		Human	PMID:22529811
Biological Process	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	SCN5A	IMP		Human	PMID:7889574
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	SCN5A	IMP		Human	PMID:7889574
Biological Process	GO:0014894	response to denervation involved in regulation of muscle adaptation	Scn5a	IMP		Rat	PMID:22336133|RGD:6484222
Biological Process	GO:0014070	response to organic cyclic compound	Scn5a	IMP	MGI:MGI:2179753	Mouse	PMID:19745168
Biological Process	GO:0086015	SA node cell action potential	SCN5A	IMP		Human	PMID:18616619
Biological Process	GO:0098719	sodium ion import across plasma membrane	Scn5a	IMP		Rat	PMID:29457789|RGD:126781740
Biological Process	GO:0035725	sodium ion transmembrane transport	SCN5A	IDA		Human	PMID:14500339
Biological Process	GO:0035725	sodium ion transmembrane transport	SCN5A	IDA		Human	PMID:19943616
Biological Process	GO:0035725	sodium ion transmembrane transport	SCN5A	IDA		Human	PMID:21051419
Biological Process	GO:0035725	sodium ion transmembrane transport	SCN5A	IMP		Human	PMID:21895525
Biological Process	GO:0035725	sodium ion transmembrane transport	SCN5A	IMP		Human	PMID:23085483
Biological Process	GO:0035725	sodium ion transmembrane transport	SCN5A	IMP		Human	PMID:26279430
Biological Process	GO:0035725	sodium ion transmembrane transport	SCN5A	IMP		Human	PMID:26392562
Biological Process	GO:0035725	sodium ion transmembrane transport	Scn5a	IMP		Mouse	PMID:24719102
Biological Process	GO:0035725	sodium ion transmembrane transport	Scn5a	IDA		Mouse	PMID:32175648
Biological Process	GO:0035725	sodium ion transmembrane transport	Scn5a	IMP		Rat	PMID:12562928|RGD:6484230
Biological Process	GO:0006814	sodium ion transport	SCN5A	IDA		Human	PMID:19074138
Biological Process	GO:0006814	sodium ion transport	SCN5A	IDA		Human	PMID:22514276
Biological Process	GO:0021537	telencephalon development	Scn5a	IEP		Rat	PMID:22331407|RGD:6484221
Biological Process	GO:0086005	ventricular cardiac muscle cell action potential	SCN5A	IMP		Human	PMID:22529811

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern