Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SARM1
  • Mouse genes Sarm1
  • Rat genes Sarm1
  • Zfish genes sarm1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sarm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003953	NAD+ nucleosidase activity	SARM1	IDA		Human	PMID:28334607
Molecular Function	GO:0003953	NAD+ nucleosidase activity	SARM1	IDA		Human	PMID:31128467
Molecular Function	GO:0003953	NAD+ nucleosidase activity	SARM1	IDA		Human	PMID:31439792
Molecular Function	GO:0003953	NAD+ nucleosidase activity	SARM1	IDA		Human	PMID:31439793
Molecular Function	GO:0003953	NAD+ nucleosidase activity	SARM1	IDA		Human	PMID:32049506
Molecular Function	GO:0003953	NAD+ nucleosidase activity	SARM1	IDA		Human	PMID:32828421
Molecular Function	GO:0003953	NAD+ nucleosidase activity	SARM1	IDA		Human	PMID:33053563
Molecular Function	GO:0003953	NAD+ nucleosidase activity	Sarm1	IDA		Mouse	MGI:MGI:6114587|PMID:28334607
Molecular Function	GO:0003953	NAD+ nucleosidase activity	sarm1	IDA		Zfish	PMID:28334607|ZFIN:ZDB-PUB-200522-29
Molecular Function	GO:0061809	NAD+ nucleotidase, cyclic ADP-ribose generating	SARM1	IDA		Human	PMID:28334607
Molecular Function	GO:0061809	NAD+ nucleotidase, cyclic ADP-ribose generating	SARM1	IDA		Human	PMID:31128467
Molecular Function	GO:0005515	protein binding	SARM1	IPI	UniProtKB:Q86XR7	Human	PMID:17258210
Molecular Function	GO:0005515	protein binding	SARM1	IPI	UniProtKB:Q99836	Human	PMID:17258210
Molecular Function	GO:0005515	protein binding	SARM1	IPI	UniProtKB:Q86XR7	Human	PMID:26592460
Molecular Function	GO:0005515	protein binding	SARM1	IPI	UniProtKB:Q99836	Human	PMID:26592460
Molecular Function	GO:0005515	protein binding	Sarm1	IPI	UniProtKB:O43187|UniProtKB:P46977|UniProtKB:Q86UT6|UniProtKB:Q96A33|UniProtKB:Q9H3K2	Mouse	MGI:MGI:5292417|PMID:21903422
Molecular Function	GO:0005515	protein binding	Sarm1	IPI	UniProtKB:P43407	Mouse	MGI:MGI:5007553|PMID:21555464
Molecular Function	GO:0005515	protein binding	Sarm1	IPI	PR:Q61831	Mouse	PMID:17724133
Cellular Component	GO:0005737	cytoplasm	Sarm1	IDA		Mouse	PMID:17724133
Cellular Component	GO:0030425	dendrite	Sarm1	IMP		Mouse	MGI:MGI:5007553|PMID:21555464
Cellular Component	GO:0005874	microtubule	Sarm1	IDA		Mouse	MGI:MGI:3760489|PMID:17724133
Cellular Component	GO:0015630	microtubule cytoskeleton	Sarm1	IDA		Mouse	PMID:17724133
Cellular Component	GO:0005741	mitochondrial outer membrane	Sarm1	IDA		Mouse	PMID:17724133
Cellular Component	GO:0005739	mitochondrion	SARM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	SARM1	IDA		Human	PMID:22145856
Cellular Component	GO:0005739	mitochondrion	Sarm1	IDA		Mouse	MGI:MGI:3760489|PMID:17724133
Cellular Component	GO:0045202	synapse	Sarm1	IDA		Mouse	MGI:MGI:5007553|PMID:21555464
Biological Process	GO:0019677	NAD catabolic process	SARM1	IDA		Human	PMID:25908823
Biological Process	GO:0019677	NAD catabolic process	SARM1	IDA		Human	PMID:27671644
Biological Process	GO:0019677	NAD catabolic process	SARM1	IDA		Human	PMID:28334607
Biological Process	GO:0019677	NAD catabolic process	SARM1	IDA		Human	PMID:31128467
Biological Process	GO:0019677	NAD catabolic process	SARM1	IDA		Human	PMID:31439792
Biological Process	GO:0019677	NAD catabolic process	SARM1	IDA		Human	PMID:31439793
Biological Process	GO:0019677	NAD catabolic process	SARM1	IDA		Human	PMID:32049506
Biological Process	GO:0019677	NAD catabolic process	SARM1	IDA		Human	PMID:32828421
Biological Process	GO:0019677	NAD catabolic process	SARM1	IDA		Human	PMID:33053563
Biological Process	GO:0019677	NAD catabolic process	Sarm1	IDA		Mouse	MGI:MGI:6114587|PMID:28334607
Biological Process	GO:0019677	NAD catabolic process	Sarm1	IMP		Mouse	MGI:MGI:6206974|PMID:27735788
Biological Process	GO:0019677	NAD catabolic process	Sarm1	IMP		Mouse	MGI:MGI:6508517|PMID:32312889
Biological Process	GO:0019677	NAD catabolic process	sarm1	IDA		Zfish	PMID:28334607|ZFIN:ZDB-PUB-200522-29
Biological Process	GO:1901216	positive regulation of neuron death	SARM1	IDA		Human	PMID:25908823
Biological Process	GO:1901216	positive regulation of neuron death	SARM1	IDA		Human	PMID:27671644
Biological Process	GO:1901216	positive regulation of neuron death	SARM1	IDA		Human	PMID:28334607
Biological Process	GO:1901216	positive regulation of neuron death	SARM1	IDA		Human	PMID:33053563
Biological Process	GO:1901216	positive regulation of neuron death	Sarm1	IMP		Mouse	MGI:MGI:6206974|PMID:27735788
Biological Process	GO:1901216	positive regulation of neuron death	Sarm1	IMP		Mouse	MGI:MGI:6508517|PMID:32312889
Biological Process	GO:0048679	regulation of axon regeneration	sarm1	IMP	ZFIN:ZDB-GENO-220616-2	Zfish	PMID:33688624
Biological Process	GO:0048814	regulation of dendrite morphogenesis	Sarm1	IMP		Mouse	MGI:MGI:5007553|PMID:21555464
Biological Process	GO:0043523	regulation of neuron apoptotic process	Sarm1	IMP	MGI:MGI:3765956	Mouse	PMID:17724133
Biological Process	GO:1901214	regulation of neuron death	Sarm1	IMP		Mouse	MGI:MGI:3760489|PMID:17724133
Biological Process	GO:0048678	response to axon injury	SARM1	IDA		Human	PMID:25908823
Biological Process	GO:0009749	response to glucose	Sarm1	IMP	MGI:MGI:3765956	Mouse	PMID:17724133

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern