Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SALL2
  • Mouse genes Sall2
  • Rat genes Sall2
  • Zfish genes sall2,si:ch211-212k18.5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sall2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	SALL2	IDA		Human	PMID:21362508
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	SALL2	IMP		Human	PMID:21362508
Molecular Function	GO:0005515	protein binding	SALL2	IPI	UniProtKB:Q8TAP6	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SALL2	IPI	UniProtKB:P08138	Human	PMID:19131967
Molecular Function	GO:0005515	protein binding	SALL2	IPI	UniProtKB:Q8NF64-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SALL2	IPI	UniProtKB:Q8TAP6	Human	PMID:25416956
Molecular Function	GO:0044877	protein-containing complex binding	Sall2	IPI	ComplexPortal:CPX-953	Mouse	MGI:MGI:4430815|PMID:16707490
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SALL2	IDA		Human	PMID:21362508
Biological Process	GO:0001654	eye development	SALL2	IDA		Human	PMID:24412933
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Sall2	IDA		Mouse	MGI:MGI:4430815|PMID:16707490
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Sall2	IDA		Mouse	MGI:MGI:4430815|PMID:16707490
Biological Process	GO:0021915	neural tube development	Sall2	IMP	MGI:MGI:3828110	Mouse	PMID:18818376
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SALL2	IMP		Human	PMID:21362508

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern