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Sall2 Gene Detail
Summary
  • Symbol
    Sall2
  • Name
    spalt like transcription factor 2
  • Synonyms
    mKIAA0360, Msal-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354373
    NCBI Gene: 50524
  • Gene Overview
    MyGene.info: SALL2
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:52311177-52328670 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.89 cM, cytoband B-C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354373
protein coding gene Chr14:52311172-52328762 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021297
protein coding gene Chr14:46352491-46371908 (-)
A/J MGP_AJ_G0021254
protein coding gene Chr14:45128018-45145461 (-)
AKR/J MGP_AKRJ_G0021230
protein coding gene Chr14:46764919-46782396 (-)
BALB/cJ MGP_BALBcJ_G0021258
protein coding gene Chr14:45241178-45258819 (-)
C3H/HeJ MGP_C3HHeJ_G0021038
protein coding gene Chr14:46565182-46584217 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021697
protein coding gene Chr14:48409150-48428900 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019241
protein coding gene Chr14:44334323-44351896 (-)
CAST/EiJ MGP_CASTEiJ_G0020557
protein coding gene Chr14:43543904-43561491 (-)
CBA/J MGP_CBAJ_G0021005
protein coding gene Chr14:49859536-49881290 (-)
DBA/2J MGP_DBA2J_G0021126
protein coding gene Chr14:44903727-44925189 (-)
FVB/NJ MGP_FVBNJ_G0021109
protein coding gene Chr14:44489582-44508414 (-)
LP/J MGP_LPJ_G0021201
protein coding gene Chr14:46947824-46967369 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021132
protein coding gene Chr14:49307312-49327058 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021724
protein coding gene Chr14:46141659-46161487 (-)
PWK/PhJ MGP_PWKPhJ_G0020306
protein coding gene Chr14:41644772-41663429 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020133
protein coding gene Chr14:42182798-42200483 (-)
WSB/EiJ MGP_WSBEiJ_G0020610
protein coding gene Chr14:46472544-46489905 (-)



Homology
more
  • Human Ortholog
    SALL2, spalt like transcription factor 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    SALL2, spalt like transcription factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    COLB, HSAL2, p150(Sal2), Sal-2, ZNF795
  • Links
    NCBI Gene ID: 6297
    neXtProt AC: NX_Q9Y467
    UniProt: Q9Y467

  • Chr Location
    14q11.2; chr14:21521080-21537216 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human SALL2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 6 genetic backgrounds
    14 phenotypes from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in no apparent abnormal phenotypes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 50524 NCBI Gene Model | MGI Sequence Detail 17494 C57BL/6J ±  kb
    transcript NM_015772 RefSeq | MGI Sequence Detail 5058 C57BL/6  
    polypeptide Q9QX96 UniProt | EBI | MGI Sequence Detail 1004 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR036236 Zinc finger C2H2 superfamily
      IPR013087 Zinc finger C2H2-type
    Molecular
    Reagents
    less
    • All nucleic 23
      Genomic 2
      cDNA 17
      Primer pair 2
      Other 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2145603, MGI:2145841
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 13
      Gene Ontology 7
      Phenotypes 10
    • Earliest
      J:59254 Kohlhase J, et al., Genomic cloning, chromosomal mapping, and expression analysis of msal-2. Mamm Genome. 2000 Jan;11(1):64-8
    • Latest
      J:231595 Gurdziel K, et al., Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory