Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RUNX1T1
  • Mouse genes Runx1t1
  • Rat genes Runx1t1
  • Zfish genes runx1t1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Runx1t1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	RUNX1T1	IPI	UniProtKB:Q05516	Human	PMID:10688654
Molecular Function	GO:0042802	identical protein binding	Runx1t1	IPI	PR:Q61909	Mouse	PMID:15509789
Molecular Function	GO:0005515	protein binding	RUNX1T1	IPI	UniProtKB:P54259	Human	PMID:10973986
Molecular Function	GO:0005515	protein binding	RUNX1T1	IPI	UniProtKB:Q5VTD9	Human	PMID:12874834
Molecular Function	GO:0005515	protein binding	RUNX1T1	IPI	UniProtKB:Q99684	Human	PMID:12874834
Molecular Function	GO:0005515	protein binding	RUNX1T1	IPI	UniProtKB:O75376	Human	PMID:17572682
Molecular Function	GO:0005515	protein binding	RUNX1T1	IPI	UniProtKB:P08047	Human	PMID:18519037
Molecular Function	GO:0005515	protein binding	RUNX1T1	IPI	UniProtKB:O75376	Human	PMID:18952841
Molecular Function	GO:0005515	protein binding	RUNX1T1	IPI	UniProtKB:Q9QX47	Human	PMID:18952841
Molecular Function	GO:0005515	protein binding	Runx1t1	IPI	PR:Q60520	Mouse	PMID:16227606
Molecular Function	GO:0005515	protein binding	Runx1t1	IPI	PR:P28033	Mouse	PMID:15509789
Molecular Function	GO:0005515	protein binding	Runx1t1	IPI	PR:O88895	Mouse	PMID:16227606
Molecular Function	GO:0005515	protein binding	Runx1t1	IPI	PR:Q60974	Mouse	PMID:16227606
Molecular Function	GO:0003714	transcription corepressor activity	RUNX1T1	IDA		Human	PMID:10688654
Cellular Component	GO:0016363	nuclear matrix	RUNX1T1	IDA		Human	PMID:10973986
Cellular Component	GO:0005654	nucleoplasm	RUNX1T1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Runx1t1	IDA		Mouse	PMID:15509789
Biological Process	GO:0045444	fat cell differentiation	Runx1t1	IDA		Mouse	PMID:15509789
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	RUNX1T1	IDA		Human	PMID:23251453
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Runx1t1	IMP		Mouse	MGI:MGI:5751611|PMID:26774823
Biological Process	GO:0051101	regulation of DNA binding	Runx1t1	IDA		Mouse	PMID:15509789
Biological Process	GO:0006355	regulation of DNA-templated transcription	Runx1t1	IDA		Mouse	PMID:15509789

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern