Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RRAGA
  • Mouse genes Rraga
  • Rat genes Rraga
  • Zfish genes rraga
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rraga

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005525	GTP binding	RRAGA	IDA		Human	PMID:14660641
Molecular Function	GO:0005525	GTP binding	RRAGA	IDA		Human	PMID:7499430
Molecular Function	GO:0005525	GTP binding	Rraga	IDA		Rat	PMID:7499430|RGD:633888
Molecular Function	GO:0003924	GTPase activity	RRAGA	IDA		Human	PMID:23723238
Molecular Function	GO:0051219	phosphoprotein binding	RRAGA	IDA		Human	PMID:8995684
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9HB90	Human	PMID:11073942
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9NQL2	Human	PMID:11073942
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q76FK4	Human	PMID:14660641
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9HB90	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9HB90	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9HB90	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9NQL2	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9P0V3	Human	PMID:22575674
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q6IAA8	Human	PMID:22980980
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:P58006	Human	PMID:25259925
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:P58043	Human	PMID:25259925
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9CYP7	Human	PMID:25259925
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q6IAA8	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q8NBW4	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9HB90	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9NQL2	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q6IAA8	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q8NBW4	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9HB90	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:P49815	Human	PMID:25936802
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:O15118,UniProtKB:Q6IAA8,UniProtKB:Q8NBW4,UniProtKB:Q9HB90	Human	PMID:28336668
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9HB90	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q9NQL2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:P63172	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q8NBW4	Human	PMID:32433612
Molecular Function	GO:0005515	protein binding	RRAGA	IPI	UniProtKB:Q64863	Human	PMID:8995684
Molecular Function	GO:0005515	protein binding	Rraga	IPI	UniProtKB:Q3TWL2	Mouse	MGI:MGI:6304515|PMID:29644770
Molecular Function	GO:0046982	protein heterodimerization activity	RRAGA	IPI	UniProtKB:Q9HB90	Human	PMID:11073942
Molecular Function	GO:0046982	protein heterodimerization activity	RRAGA	IPI	UniProtKB:Q9HB90	Human	PMID:14660641
Molecular Function	GO:0042803	protein homodimerization activity	RRAGA	IDA		Human	PMID:14660641
Molecular Function	GO:0031625	ubiquitin protein ligase binding	RRAGA	IPI	UniProtKB:Q8N8N0	Human	PMID:25936802
Cellular Component	GO:0005737	cytoplasm	RRAGA	IDA		Human	PMID:11073942
Cellular Component	GO:0005737	cytoplasm	RRAGA	IDA		Human	PMID:9394008
Cellular Component	GO:0005765	lysosomal membrane	RRAGA	HDA		Human	PMID:17897319
Cellular Component	GO:0005764	lysosome	RRAGA	IDA		Human	PMID:20381137
Cellular Component	GO:0005654	nucleoplasm	RRAGA	IDA		Human	PMID:8995684
Cellular Component	GO:0005634	nucleus	RRAGA	IDA		Human	PMID:11073942
Biological Process	GO:0008219	cell death	RRAGA	IDA		Human	PMID:9394008
Biological Process	GO:0034198	cellular response to amino acid starvation	RRAGA	IMP		Human	PMID:25936802
Biological Process	GO:0071230	cellular response to amino acid stimulus	RRAGA	IMP		Human	PMID:20381137
Biological Process	GO:0022010	central nervous system myelination	rraga	IGI	ZFIN:ZDB-GENO-190307-19	Zfish	PMID:30399334
Biological Process	GO:0010507	negative regulation of autophagy	RRAGA	IMP		Human	PMID:25936802
Biological Process	GO:1904263	positive regulation of TORC1 signaling	RRAGA	IMP		Human	PMID:25936802
Biological Process	GO:0008104	protein localization	RRAGA	IMP		Human	PMID:20381137
Biological Process	GO:2000425	regulation of apoptotic cell clearance	rraga	IMP	ZFIN:ZDB-GENO-170206-2	Zfish	PMID:26774477
Biological Process	GO:1905671	regulation of lysosome organization	rraga	IMP	ZFIN:ZDB-GENO-170206-2	Zfish	PMID:26774477
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	RRAGA	IDA		Human	PMID:8995684

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern