Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RO60
  • Mouse genes Ro60
  • Rat genes Ro60
  • Zfish genes ro60
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ro60

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003723	RNA binding	RO60	IDA		Human	PMID:26382853
Molecular Function	GO:0003723	RNA binding	Ro60	IDA		Mouse	PMID:14680639
Molecular Function	GO:0030620	U2 snRNA binding	Ro60	IDA		Mouse	PMID:14680639
Cellular Component	GO:0005737	cytoplasm	Ro60	IDA		Mouse	PMID:14680639
Cellular Component	GO:0005829	cytosol	RO60	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	RO60	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RO60	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ro60	IDA		Mouse	PMID:14680639
Cellular Component	GO:1990904	ribonucleoprotein complex	RO60	IDA		Human	PMID:17289661
Cellular Component	GO:1990904	ribonucleoprotein complex	Ro60	IDA		Mouse	PMID:14680639
Biological Process	GO:0035457	cellular response to interferon-alpha	RO60	IDA		Human	PMID:26382853
Biological Process	GO:0060271	cilium assembly	Ro60	IMP		Mouse	PMID:21289087
Biological Process	GO:0002520	immune system development	Ro60	IMP	MGI:MGI:2670227	Mouse	PMID:12788971
Biological Process	GO:0010468	regulation of gene expression	RO60	IDA		Human	PMID:26382853
Biological Process	GO:0009411	response to UV	Ro60	IDA		Mouse	PMID:14680639
Biological Process	GO:0009411	response to UV	Ro60	IMP	MGI:MGI:2670227	Mouse	PMID:12788971
Biological Process	GO:0007224	smoothened signaling pathway	Ro60	IMP		Mouse	PMID:21289087

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern